Duration of intra-aortic balloon pump use and related complications.

Acute cardiac care Pub Date : 2014-06-01 Epub Date: 2014-03-21 DOI:10.3109/17482941.2014.889311
Konstantinos Dean Boudoulas, Theodore Bowen, Andrew Pederzolli, Kyle Pfahl, Vincent J Pompili, Ernest L Mazzaferri
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引用次数: 14

Abstract

Background: Intra-aortic balloon pump (IABP) use may be associated with complications; however, in certain patients with ST-elevation myocardial infarction (STEMI) with hemodynamic instability refractory to medical management its use may become necessary.

Methods: 36 STEMI patients with IABP placement for hemodynamic instability after percutaneous coronary intervention were studied. IABP duration ranged from one to seven days (median two days). Based on median time, patients were divided into two groups: IABP duration ≤ 2 days (n = 27) or > 2 days (n = 9). Vascular complications and incidence of bleeding were compared.

Results: Mean IABP duration was 1.4 ± 0.5 and 4.1 ± 1.3 days in ≤ 2 day and > 2 day groups, respectively (P < 0.01). Glycoprotein IIb/IIIa inhibitor and anti-coagulation use was not significantly different between groups. Mean duration of anti-coagulation was 1.9 ± 1.2 and 4.5 ± 1.3 days in ≤ 2 day and > 2 day groups, respectively (P < 0.05). Complications (vascular, access site bleeding, gastrointestinal bleeding) were significantly greater in > 2 day group (66%) compared to ≤ 2 day group (18%; P < 0.05).

Conclusions: When an IABP was used for more than two days complications significantly increased. The clinical implications of the study will be strengthened if the findings are confirmed in a prospective study with a larger number of patients.

主动脉内球囊泵使用时间及相关并发症。
背景:主动脉内球囊泵(IABP)的使用可能与并发症相关;然而,在某些st段抬高型心肌梗死(STEMI)伴有血流动力学不稳定且药物治疗难治性的患者中,可能需要使用它。方法:对36例经皮冠状动脉介入治疗后放置IABP治疗血流动力学不稳定的STEMI患者进行研究。IABP持续时间为1 - 7天(中位数为2天)。根据中位时间将患者分为IABP持续时间≤2天(n = 27)和> 2天(n = 9)两组,比较血管并发症和出血发生率。结果:≤2天组和> 2天组的平均IABP持续时间分别为1.4±0.5天和4.1±1.3天(P < 0.01)。两组间糖蛋白IIb/IIIa抑制剂和抗凝使用无显著差异。≤2 d组和> 2 d组的平均抗凝时间分别为1.9±1.2天和4.5±1.3 d (P < 0.05)。并发症(血管、通路出血、胃肠道出血)> 2天组(66%)明显高于≤2天组(18%;P < 0.05)。结论:当IABP使用超过2天时,并发症明显增加。如果研究结果在更多患者的前瞻性研究中得到证实,该研究的临床意义将得到加强。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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