Early versus Late Surgical Treatment for Neurogenic Thoracic Outlet Syndrome.

ISRN Neurology Pub Date : 2013-09-10 eCollection Date: 2013-01-01 DOI:10.1155/2013/673020
Jasem Yousef Al-Hashel, Ashraf Ali M A El Shorbgy, Samar Farouk Ahmed, Rawhia R Elshereef
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Abstract

Objectives. To compare the outcome of early surgical intervention versus late surgical treatment in cases of neurogenic thoracic outlet syndrome (NTOS). Design. Prospective study. Settings. Secondary care (Al-Minia University Hospital, Egypt) from 2007 to 2010. Participants. Thirty-five patients of NTOS (25 women and 10 men, aged 20-52 years), were classified into 2 groups. First group (20 patients) was operated within 3 months of the onset and the second group (15 patients) was operated 6 months after physiotherapy. Interventions. All patients were operated via supraclavicular surgical approach. Outcomes Measures. Both groups were evaluated clinically and, neurophysiologically and answered the disabilities of the arm, shoulder, and hand (DASH) questionnaire preoperatively and 6 months after the surgery. Results. Paraesthesia, pain, and sensory nerve action potential (SNAP) of ulnar nerve were significantly improved in group one. Muscle weakness and denervation in electromyography EMG were less frequent in group one. The postoperative DASH score improved in both groups but it was less significant in group two (P < .001 in group 1 and P < .05 in group 2). Conclusions. Surgical treatment of NTOS improves functional disability and stop degeneration of the nerves. Early surgical treatment decreases the occurrence of muscle wasting and denervation of nerves compared to late surgery.

神经源性胸廓出口综合征的早期手术治疗与晚期手术治疗。
研究目的比较神经源性胸廓出口综合征(NTOS)病例中早期手术干预与晚期手术治疗的效果。设计。前瞻性研究。设置。二级医疗机构(埃及 Al-Minia 大学医院),2007 年至 2010 年。参与者。35 名 NTOS 患者(25 名女性和 10 名男性,年龄在 20-52 岁之间)分为两组。第一组(20 名患者)在发病 3 个月内进行手术,第二组(15 名患者)在物理治疗 6 个月后进行手术。干预措施所有患者均通过锁骨上手术方式进行手术。结果测量。对两组患者进行临床和神经生理学评估,并在术前和术后 6 个月回答手臂、肩部和手部残疾(DASH)问卷。结果显示第一组患者的尺神经麻痹、疼痛和感觉神经动作电位(SNAP)明显改善。第一组的肌无力和肌电图变性的发生率较低。两组的术后 DASH 评分均有所改善,但第二组的改善幅度较小(第一组 P < 0.001,第二组 P < 0.05)。结论手术治疗 NTOS 可改善功能障碍,阻止神经退化。与晚期手术相比,早期手术治疗可减少肌肉萎缩和神经支配的发生。
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