Negative pressure wound therapy in infants and children: a single-institution experience.

The Journal of surgical research Pub Date : 2013-09-01 Epub Date: 2013-06-04 DOI:10.1016/j.jss.2013.05.056
Rebecca M Rentea, Kimberly K Somers, Laura Cassidy, Jessica Enters, Marjorie J Arca
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引用次数: 27

Abstract

Background: Information regarding the use of negative pressure wound therapy (NPWT) in the pediatric population is limited. Because of adverse outcomes in adult patients, the Food and Drug Administration issued a warning in 2011 about the use of NPWT in infants and children.

Methods: We performed an institutional review board-approved, single-institution, retrospective review of pediatric patients who had undergone NPWT from 2007-2011. We collected the types of wounds for which NPWT was initiated, the NPWT outcomes, and the complications encountered.

Results: The data from 290 consecutive patients were reviewed. Their average age was 9.3 y (range 12 d to 18 y), and their average weight was 46.5 kg (range 1.1-177). Of the wounds, 66% were classified as acute, 10% as chronic, and 24% as traumatic. The two most common indications were surgical wound dehiscence (n = 47) and skin grafting (n = 41). NPWT was used in 15 wounds containing surgical hardware, with 2 devices requiring eventual removal. NPWT was used for a median of 9 d per patient (two dressing changes). Complications occurred in 5 patients (1.7%). Documentation problems were noted in 44 patients. After NPWT, about one-third of the patients (n = 95 patients) were able to undergo delayed primary closure.

Conclusions: NPWT is an effective adjunct in wound healing and closure in the pediatric population, with no mortality ascribed to NPWT. Also, the complication rates were low.

婴儿和儿童负压伤口治疗:单一机构的经验。
背景:关于负压伤口治疗(NPWT)在儿科人群中的应用的信息是有限的。由于对成年患者的不良后果,美国食品和药物管理局(Food and Drug Administration)在2011年发布了关于在婴儿和儿童中使用NPWT的警告。方法:我们对2007-2011年接受NPWT的儿科患者进行了机构审查委员会批准的单机构回顾性审查。我们收集了NPWT开始的伤口类型,NPWT的结果,以及遇到的并发症。结果:回顾了290例连续患者的资料。平均年龄9.3岁(12 ~ 18岁),平均体重46.5 kg(1.1 ~ 177岁)。在这些伤口中,66%为急性,10%为慢性,24%为创伤性。两个最常见的适应症是手术伤口裂开(n = 47)和植皮(n = 41)。NPWT用于15个包含手术器械的伤口,其中2个需要最终移除。NPWT的平均使用时间为每位患者9天(两次换药)。并发症5例(1.7%)。在44例患者中发现文件问题。NPWT后,约三分之一的患者(n = 95例)能够延迟进行原发性关闭。结论:NPWT是儿童伤口愈合和闭合的有效辅助手段,没有死亡归因于NPWT。此外,并发症发生率低。
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