The Relationships between Cholesterol and Suicide: An Update.

ISRN Psychiatry Pub Date : 2012-12-23 Print Date: 2012-01-01 DOI:10.5402/2012/387901

Domenico De Berardis, Stefano Marini, Monica Piersanti, Marilde Cavuto, Giampaolo Perna, Alessandro Valchera, Monica Mazza, Michele Fornaro, Felice Iasevoli, Giovanni Martinotti, Massimo Di Giannantonio

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引用次数: 68

Abstract

Cholesterol is a core component of the central nervous system, essential for the cell membrane stability and the correct functioning of neurotransmission. It has been observed that cholesterol may be somewhat associated with suicidal behaviours. Therefore, the aim of this paper was to elucidate current facts and views about the role of cholesterol levels in mood disorders. The majority of the studies reviewed in the present paper suggest an interesting relationship between cholesterol (especially lower levels) and suicidality. On the other hand, particularly during the last years, relationships between serum cholesterol and suicidality were doubted on the basis of some recent studies that have not found any correlation. However, the debate on relationships between cholesterol and suicide is open and longitudinal studies on a larger sample of patients are needed to further clarify this important issue.

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胆固醇与自杀之间的关系:最新进展。

胆固醇是中枢神经系统的核心成分，对细胞膜的稳定和神经传递的正常运作至关重要。据观察，胆固醇可能与自杀行为有某种联系。因此，本文的目的是阐明目前有关胆固醇水平在情绪障碍中的作用的事实和观点。本文回顾的大多数研究表明，胆固醇(尤其是低水平)与自杀之间存在有趣的关系。另一方面，特别是在最近几年，血清胆固醇和自杀之间的关系受到质疑，因为最近的一些研究没有发现任何相关性。然而，关于胆固醇和自杀之间关系的争论是开放的，需要对更大样本的患者进行纵向研究，以进一步澄清这一重要问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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ISRN Psychiatry

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