Effects of atropine on the accommodative system: parameters to consider in its use for penalization treatment of amblyopia.

Binocular vision & strabology quarterly, Simms-Romano's Pub Date : 2013-01-01

Noelle Matta, David I Silbert

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Abstract

Purpose: We set out to determine the accommodative effects of Atropine on the visual system.

Methods: A prospective study was done on a normal eye in a 31-year-old cooperative adult. One drop of 1% Atropine was instilled and the effect on accommodation, near visual acuity and pupil size was recorded. Accommodation was measured at 1/3 of a meter utilizing the Grand Seiko Auto Refractor. Near visual acuity was measured with the PEDIG ATS 4 near visual acuity test at a set distance of 16 inches.

Results: Atropine caused its greatest effect to accommodation, and to pupil size, 3 hours after installation. Curiously, the greatest effect on near visual acuity was seen 27 hours after instillation at which time it dropped to 20/80. Near visual acuity had improved to 20/25 on day 4. Accommodation returned to normal 8 days after instillation and pupil size returned to normal 12 days after instillation.

Conclusion: One drop of Atropine affected accommodation for 8 days. Despite this, near vision returned to 20/20 by day 5. These findings may impact how Atropine penalization is prescribed to treat amblyopia both to maximize effectiveness and minimize its impact on school performance.

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阿托品对调节系统的影响:弱视惩罚性治疗中应考虑的参数。

目的:我们开始确定阿托品对视觉系统的调节作用。方法:对一名31岁的合作性成人的正常眼进行前瞻性研究。滴注1%阿托品1滴，记录对调节、近视力和瞳孔大小的影响。住宿测量在1/3米利用大精工自动折射。近视敏锐度采用PEDIG ATS 4近视敏锐度测试，距离为16英寸。结果:阿托品在给药后3小时对瞳孔调节和瞳孔大小的影响最大。奇怪的是，注射后27小时对近视力的影响最大，此时视力下降到20/80。第4天，近视力改善至20/25。8天后调节功能恢复正常，12天后瞳孔大小恢复正常。结论:1滴阿托品影响8天的住宿。尽管如此，第5天近视恢复到20/20。这些发现可能会影响如何使用阿托品惩罚来治疗弱视，以最大限度地提高效果，并将其对学校表现的影响降到最低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Binocular vision & strabology quarterly, Simms-Romano's

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