Vestibular function in superficial siderosis.

Q2 Medicine

BMC Ear, Nose and Throat Disorders Pub Date : 2013-04-23 eCollection Date: 2013-01-01 DOI:10.1186/1472-6815-13-5

Toru Miwa, Ryosei Minoda, Hidetake Matsuyoshi

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引用次数: 9

Abstract

Background: Superficial siderosis (SS) is caused by repeated or continuous bleeding into the subarachnoid space that results in iron from hemoglobin (hemosiderin) being deposited on the surface of the brain. Clinically, the condition is characterized by sensorineural deafness, ataxia, and pyramidal signs. However the mechanism of peripheral vestibular disturbance was not revealed. We show the vestibular function of SS patients, and shed light on saccule-inferior vestibular nerve.

Methods: Over the past 9 years, 5 patients were definitively diagnosed with SS by MRI in our department. These patients were subjected to balance testing.

Results: Vestibular evoked myogenic potential (VEMP) was observed in patients who had suffered from SS for a short period but tended to be diminished or absent in patients who had suffered from the condition for a longer period.

Conclusions: These findings in SS patients suggest that saccule-inferior vestibular function is maintained at early stages of the disorder. Our study may help to clarify the mechanism of SS.

Abstract Image

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浅表性铁沉着的前庭功能。

背景:浅表性铁沉着症(SS)是由反复或持续的蛛网膜下腔出血引起的，导致血红蛋白中的铁(含铁血黄素)沉积在脑表面。临床表现为感音神经性耳聋、共济失调和锥体征。但前庭周围神经紊乱的发生机制尚不清楚。我们展示了SS患者的前庭功能，并揭示了前庭下囊神经。方法:我科9年来通过MRI确诊SS患者5例。这些病人接受了平衡测试。结果:前庭诱发肌源电位(VEMP)在短时间SS患者中存在，而在长时间SS患者中有减弱或不存在的趋势。结论:SS患者的这些发现表明，在疾病的早期阶段，前庭系统的球囊-下功能是维持的。我们的研究可能有助于阐明SS的机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Ear, Nose and Throat Disorders Medicine-Otorhinolaryngology

CiteScore

3.30

自引率

0.00%

发文量

期刊介绍： BMC Ear, Nose and Throat Disorders is an open access journal publishing original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of ear, nose and throat disorders, as well as related molecular genetics, pathophysiology, and epidemiology. BMC Ear, Nose and Throat Disorders (ISSN 1472-6815) is indexed/tracked/covered by PubMed, CAS, EMBASE, Scopus and Google Scholar.