Lumbar microdiscectomy and lumbar decompression improve functional outcomes and depression scores.

Suzanne Tharin, Eric Mayer, Ajit Krishnaney
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引用次数: 23

Abstract

Study design:  Retrospective review.

Introduction:  Lumbar radiculopathy and claudicant leg pain are common degenerative spinal conditions often treated by elective microdiscectomy or decompression. Published outcome data for these procedures have focused on improvement in pain scores, and not on grounded functional outcome or depression scores.1,2,3 Moreover, depression is considered by many surgeons to be a red flag for poor outcome for surgical treatment. We asked what effect lumbar microdiscectomy and laminectomy procedures had on functional outcome and depression scores in our clinical population.

Methods:  Beginning in January 2010, the following outcome data were prospectively gathered before and after surgery from all patients at the Cleveland Clinic undergoing either lumbar microdiscectomy or lumbar decompression: EQ-5D (EuroQOL, quality-of-life measure), PHQ-9 (measure of depressive symptoms), PDQ (pain disability questionnaire), and Rankin scores (disability or dependence in daily activities).

Results:  The mean EuroQOL scores improved by 35% (from 0.4-0.75 of a maximum of 1.0) for both microdiscectomy and lumbar laminectomies. The mean PHQ-9 scores (measure of depressive symptoms) significantly improved for most patients undergoing either procedure. In line with previously published reports, we also found improvement in Rankin scores and Pain Disability Questionnaire scores.

Conclusions:  Our outcome data indicate that microdiscectomy and lumbar decompression not only reduce disability and pain but also improve depressive symptoms and overall quality of life for patients. These findings support operative treatment of lumbar radiculopathy and neurogenic claudication including treatment performed in the depressed population.

腰椎微椎间盘切除术和腰椎减压可改善功能预后和抑郁评分。
研究设计:回顾性研究。腰椎神经根病和跛腿痛是常见的退行性脊柱疾病,通常通过选择性显微椎间盘切除术或减压来治疗。已发表的结果数据集中于疼痛评分的改善,而不是基于功能结果或抑郁评分。此外,抑郁症被许多外科医生认为是手术治疗效果不佳的危险信号。我们询问腰椎微椎间盘切除术和椎板切除术对临床人群的功能结局和抑郁评分有什么影响。方法:从2010年1月开始,前瞻性地收集克利夫兰诊所所有接受腰椎微椎间盘切除术或腰椎减压的患者手术前后的结果数据:EQ-5D (EuroQOL,生活质量测量)、PHQ-9(抑郁症状测量)、PDQ(疼痛残疾问卷)和Rankin评分(日常活动的残疾或依赖性)。结果:显微椎间盘切除术和腰椎椎板切除术的平均EuroQOL评分提高了35%(从0.4-0.75提高到1.0)。平均PHQ-9评分(抑郁症状的衡量指标)在接受任何一种治疗的大多数患者中都有显著改善。与先前发表的报告一致,我们还发现Rankin评分和疼痛残疾问卷评分有所改善。结论:我们的结果数据表明,显微椎间盘切除术和腰椎减压术不仅可以减轻残疾和疼痛,还可以改善患者的抑郁症状和整体生活质量。这些发现支持手术治疗腰椎神经根病和神经源性跛行,包括对抑郁症患者的治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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