Major themes for 2011 in cardiovascular anesthesia and intensive care.

H Riha, P Patel, E Valentine, B Lane, J G T Augoustides
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Abstract

The past year has witnessed major advances in of cardiovascular anesthesia and intensive care. Perioperative interventions such as anesthetic design, inotrope choice, glycemic therapy, blood management, and noninvasive ventilation have significant potential to enhance perioperative outcomes even further.The major theme for 2011 is the international consensus conference that focused on ancillary interventions likely to reduce mortality in cardiac anesthesia and intensive care. This landmark conference prioritized volatile anesthetics, levosimendan, and insulin therapy for their promising life-saving perioperative potential. Although extensive evidence has demonstrated the cardioprotective effects of volatile anesthetics, levosimendan as well as glucose, insulin and potassium therapy, the clinical relevance of these beneficial effects remains to be fully elucidated. Furthermore, controversy still persists about how tight perioperative glucose control should be in adult cardiac surgery because of the risk of hypoglycemia.A second major theme in 2011 has been perioperative hemostasis with the release of multispecialty guidelines. Furthermore, hemostatic agents such as recombinant factor VIIa and tranexamic acid have been studied intensively, even in the setting of major non-cardiac surgery. This review then highlights the remaining two major themes for 2011, namely the expanding role of noninvasive ventilation in our specialty and the formation of the Roland Hetzer International Cardiothoracic and Vascular Surgery Society.In conclusion, it is time for large adequately powered multicenter trials to test whether prioritized perioperative interventions truly reduce mortality and morbidity in cardiac surgical patients. This essential paradigm shift represents a major clinical opportunity for the global cardiovascular anesthesia and critical care community.

2011年心血管麻醉和重症监护的主要主题。
在过去的一年里,心血管麻醉和重症监护取得了重大进展。围手术期干预措施,如麻醉设计、肌力选择、血糖治疗、血液管理和无创通气,具有进一步提高围手术期预后的显著潜力。2011年的主要主题是国际共识会议,重点关注可能降低心脏麻醉和重症监护死亡率的辅助干预措施。这次具有里程碑意义的会议优先考虑了挥发性麻醉剂、左西孟旦和胰岛素治疗,因为它们有可能挽救围手术期的生命。尽管大量证据已经证明了挥发性麻醉剂、左西孟旦以及葡萄糖、胰岛素和钾治疗的心脏保护作用,但这些有益作用的临床相关性仍有待充分阐明。此外,由于低血糖的风险,关于成人心脏手术围手术期血糖控制的严格程度仍存在争议。随着多专业指南的发布,2011年的第二个主要主题是围手术期止血。此外,止血剂如重组因子VIIa和氨甲环酸已被深入研究,甚至在重大非心脏手术的设置。这篇综述强调了2011年剩下的两个主要主题,即无创通气在我们专业中的作用扩大,以及Roland Hetzer国际心胸血管外科学会的成立。总之,是时候进行大规模的多中心试验来检验优先围手术期干预是否真的能降低心脏手术患者的死亡率和发病率。这种重要的模式转变代表了全球心血管麻醉和重症监护社区的重大临床机会。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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