Bacteriophages for managing Shigella in various clinical and non-clinical settings.

Bacteriophage Pub Date : 2013-01-01 Epub Date: 2013-05-21 DOI:10.4161/bact.25098
Lawrence D Goodridge
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引用次数: 24

Abstract

The control of shigellosis in humans enjoys a prominent position in the history of bacteriophage therapy. d'Herelle first demonstrated the efficacy of phage therapy by curing 4 patients of shigellosis, and several subsequent studies confirmed the ability of phages to reduce Shigella based infection. Shigella spp continue to cause millions of illnesses and deaths each year and the use of phages to control the disease in humans and the spread of the bacteria within food and water could point the way forward to the effective management of an infectious disease with global influence.

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在各种临床和非临床环境中用于控制志贺氏菌的噬菌体。
人类志贺氏菌病的控制在噬菌体治疗史上占有重要地位。d'Herelle首先通过治愈4例志贺氏菌病患者证明了噬菌体治疗的有效性,随后的几项研究证实了噬菌体减少志贺氏菌感染的能力。志贺氏菌每年继续造成数百万人患病和死亡,利用噬菌体控制人类患病和细菌在食物和水中的传播,可能为有效管理具有全球影响的传染病指明方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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