Basal cell carcinoma: a single-center experience.

ISRN Dermatology Pub Date : 2012-01-01 Epub Date: 2012-12-22 DOI:10.5402/2012/246542
Ozan Luay Abbas, Huseyin Borman
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Abstract

Background. Basal cell carcinoma comprises the vast majority of skin cancers. It predominantly affects fair-skinned individuals, and its incidence is rising rapidly. Etiology may be multifactorial, but sun exposure appears to play a critical role. When detected early, the prognosis is excellent. Thus appropriate diagnosis, treatment, and surveillance are of utmost importance. Methods. From January 1994 to May 2012, 518 basal cell carcinomas were excised in our clinic. Data were collected retrospectively. Results. During 18-year period, 518 BCCs were excised from 486 patients. Most of the patients were males with a median age of 65.6 years. Most of the basal cell carcinomas were located in the head region. Nodular histological subtype dominated our series. Six percent of the excised lesions required reexcision because of involved margins. Our recurrence rate was 6.94% with the nose and the periauricular and periocular regions being the most common sites of occurrence. Conclusion. Although there is relatively low attributable mortality, the morbidity and cost of treatment are significant. A large body of information serves as a foundation for oncologic principles, diagnosis methods, surgical excisions, follow-up protocols, and reconstructive methodologies that are currently in use. Surgical ablation remains the mainstay of treatment.

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基底细胞癌:单中心经验。
背景:基底细胞癌占皮肤癌的绝大多数。基底细胞癌占皮肤癌的绝大多数。它主要影响皮肤白皙的人,发病率正在迅速上升。病因可能是多因素的,但阳光照射似乎起着关键作用。如果及早发现,预后良好。因此,适当的诊断、治疗和监控至关重要。研究方法从 1994 年 1 月到 2012 年 5 月,本诊所共切除了 518 例基底细胞癌。数据以回顾性方式收集。结果。18 年间,共从 486 名患者身上切除了 518 个基底细胞癌。大部分患者为男性,中位年龄为 65.6 岁。大多数基底细胞癌位于头部。结节型组织学亚型在我们的系列研究中占主导地位。6%的切除病灶因边缘受累而需要再次切除。复发率为6.94%,鼻部、耳周和眼周是最常见的复发部位。结论。虽然可归因的死亡率相对较低,但发病率和治疗费用却很高。大量信息为目前使用的肿瘤学原理、诊断方法、手术切除、随访方案和重建方法奠定了基础。手术消融仍然是治疗的主要方法。
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