What, in Fact, Is the Evidence That Vaccinating Healthcare Workers against Seasonal Influenza Protects Their Patients? A Critical Review.

International journal of family medicine Pub Date : 2012-01-01 Epub Date: 2012-11-11 DOI:10.1155/2012/205464
Zvi Howard Abramson
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Abstract

Background and Methods. Vaccination of all healthcare workers is widely recommended by health authorities and medical institutions and support for mandatory vaccination is increasing. This paper presents the relevant literature and examines the evidence for patient benefit from healthcare worker vaccination. Articles identified by Medline searches and citation lists were inspected for internal and external validity. Emphasis was put on RCTs. The literature on self-protection from vaccination is also presented. Results. Published research shows that personal benefit from vaccinating healthy nonelderly adults is small and there is no evidence that it is any different for HCWs. The studies aiming to prove the widespread belief that healthcare worker vaccination decreases patient morbidity and mortality are heavily flawed and the recommendations for vaccination biased. No reliable published evidence shows that healthcare workers' vaccination has substantial benefit for their patients-not in reducing patient morbidity or mortality and not even in increasing patient vaccination rates. Conclusion. The arguments for uniform healthcare worker influenza vaccination are not supported by existing literature. The decision whether to get vaccinated should, except possibly in extreme situations, be that of the individual healthcare worker, without legal, institutional, or peer coercion.

为医护人员接种季节性流感疫苗可保护患者的证据究竟是什么?批判性评论。
背景与方法。卫生当局和医疗机构广泛建议所有医护人员接种疫苗,对强制接种的支持也在不断增加。本文介绍了相关文献,并研究了医护人员接种疫苗对患者有益的证据。对通过 Medline 搜索和引用列表确定的文章进行了内部和外部有效性检查。重点放在 RCT 上。此外,还介绍了有关接种疫苗的自我保护的文献。结果。已发表的研究表明,健康的非老年人从接种疫苗中获得的个人利益很小,没有证据表明对医护人员而言有任何不同。旨在证明 "医护人员接种疫苗可降低患者发病率和死亡率 "这一普遍观点的研究存在严重缺陷,对接种疫苗的建议也有失偏颇。没有任何可靠的公开证据显示医护人员接种疫苗对患者有实质性的益处--在降低患者发病率或死亡率方面,甚至在提高患者疫苗接种率方面。结论。现有文献并不支持医护人员统一接种流感疫苗的论点。除极端情况外,是否接种疫苗应由医护人员个人决定,而不应受到法律、机构或同行的胁迫。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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