Hepatitis C virus: a critical appraisal of new approaches to therapy.

Hepatitis research and treatment Pub Date : 2012-01-01 Epub Date: 2012-10-08 DOI:10.1155/2012/138302
David R Nelson, Donald M Jensen, Mark S Sulkowski, Greg Everson, Michael W Fried, Stuart C Gordon, Ira Jacobson, Nancy S Reau, Kenneth Sherman, Nora Terrault, David Thomas
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引用次数: 6

Abstract

The HCV council 2011 convened 11 leading clinicians and researchers in hepatitis C virus from academic medical centers in the United States to provide a forum for the practical and comprehensive evaluation of current data regarding best practices for integrating new direct-acting antiviral agents into existing treatment paradigms. The council investigated 10 clinical practice statements related to HCV treatment that reflect key topical areas. Faculty members reviewed and discussed the data related to each statement, and voted on the nature of the evidence and their level of support for each statement. In this new era of DAAs, a comprehensive and critical analysis of the literature is needed to equip clinicians with the knowledge necessary to design, monitor, and modify treatment regimens in order to optimize patient outcomes.

Abstract Image

丙型肝炎病毒:对治疗新方法的关键评价。
2011年丙型肝炎委员会召集了来自美国学术医疗中心的11位丙型肝炎病毒的主要临床医生和研究人员,为将新的直接作用抗病毒药物纳入现有治疗范例的最佳做法的当前数据的实际和全面评估提供了一个论坛。委员会调查了10项与HCV治疗相关的临床实践声明,这些声明反映了关键的主题领域。教师们审查和讨论与每个陈述相关的数据,并对证据的性质和他们对每个陈述的支持程度进行投票。在DAAs的新时代,需要对文献进行全面和批判性的分析,以使临床医生具备设计、监测和修改治疗方案所需的知识,从而优化患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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