The Antibacterial Efficacy of Biopure MTAD in Root Canal Contaminated with Enterococcus faecalis.

ISRN dentistry Pub Date : 2012-01-01 Epub Date: 2012-08-01 DOI:10.5402/2012/390526
Blerim Kamberi, Donika Bajrami, Miranda Stavileci, Shuhreta Omeragiq, Fatmir Dragidella, Ferit Koçani
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引用次数: 16

Abstract

Aim. The purpose of this in vitro study was to assess the antimicrobial efficacy of Biopure MTAD against E. faecalis in contaminated root canals. Materials and Methods. Forty-two single rooted extracted human teeth were inoculated with E. faecalis and incubated for four weeks. The samples were divided in two control and five experimental groups irrigated with 1.5% sodium hypochlorite solution (NaOCl); 3% NaOCl; BioPure MTAD; 1.5% NaOCl/17% EDTA; or 3% NaOCl/17% EDTA. After a one-week incubation, complete disinfection was confirmed by the absence of turbidity in the incubation media. Dentin shavings were taken from samples with no turbidity to verify whether E. faecalis was present in dentin tubules. Results were analyzed statistically using Fisher's exact test, with the level of significance set at P < 0.05. Results. Statistical analysis of the data obtained at Day 7 and after dentin shaving analysis showed that BioPure MTAD had significantly greater antibacterial activity than 1.5% NaOCl, 1.5% NaOCl/17% EDTA and 3% NaOCl/17% EDTA. No significant difference was detected between MTAD and 3% NaOCl. Conclusions. These findings suggest that BioPure MTAD possesses superior bactericidal activity compared with NaOCl and EDTA against E. faecalis.

生物纯MTAD对粪肠球菌污染根管的抗菌效果。
的目标。本体外研究的目的是评估Biopure MTAD对污染根管中的粪肠杆菌的抗菌效果。材料与方法。将42颗拔除的人单根牙齿接种粪肠杆菌,培养4周。将样品分为2个对照组和5个试验组,用1.5%次氯酸钠溶液(NaOCl)灌溉;NaOCl 3%;BioPure MTAD;1.5% NaOCl/17% EDTA;或3% NaOCl/17% EDTA。经过一周的培养后,通过培养培养基中没有浑浊来证实完全消毒。从没有浑浊的样品中提取牙本质刨花,以验证粪肠球菌是否存在于牙本质小管中。结果采用Fisher精确检验进行统计学分析,显著性水平为P < 0.05。结果。对第7天和牙本质剃须分析后的数据进行统计分析表明,BioPure MTAD的抗菌活性显著高于1.5% NaOCl、1.5% NaOCl/17% EDTA和3% NaOCl/17% EDTA。MTAD与3% NaOCl之间无显著差异。结论。这些结果表明,与NaOCl和EDTA相比,BioPure MTAD对粪肠杆菌具有更强的杀菌活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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