Mortality and survival rates after elective hepatic surgery in a low-volume centre are comparable to those of high-volume centres.

ISRN surgery Pub Date : 2012-01-01 Epub Date: 2012-07-31 DOI:10.5402/2012/783932
I E Nygård, K Lassen, J Kjæve, A Revhaug
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引用次数: 10

Abstract

Background. Over the last decades, liver resection has become a frequently performed procedure in western countries because of its acceptance as the most effective treatment for patients with selected cases of metastatic tumours. The purpose of this study was to evaluate the results after hepatic resections performed electively in our centre since 1979 and compare the results to those of larger high-volume centres. Methods. Medical records of all patients who underwent liver resection from January 1979 to December 2011 were reviewed. Disease-free survival and overall survival were determined by Kaplan-Meier analysis. Risk factors for complications were tested with the log-rank test and the Cox proportional hazard model. Complications were classified according to the modified Clavien classification system. Results. 290 elective liver resections were performed between January 1979 and December 2011. There were 171 males (59.0%) and 119 females (41.0%). Median age was 63 years, range 1-87. Overall survival ranged from 0 to 383 months, with a median of 31 months. Five-year survival rate for patients who underwent liver resection for colorectal metastases was 35.8% (34/95). Discussion. Hepatic resections are safely performed at a low-volume centre, with regard to perioperative- and in-house mortality and 5-year survival rates.

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小容量中心择期肝手术后的死亡率和存活率与大容量中心相当。
背景。在过去的几十年里,肝脏切除术已经成为西方国家经常进行的手术,因为它被认为是治疗转移性肿瘤患者最有效的方法。本研究的目的是评估自1979年以来本中心选择性肝切除术后的结果,并将结果与较大的高容量中心的结果进行比较。方法。回顾了1979年1月至2011年12月所有肝切除术患者的医疗记录。通过Kaplan-Meier分析确定无病生存期和总生存期。并发症的危险因素采用log-rank检验和Cox比例风险模型进行检验。根据改良的Clavien分类系统对并发症进行分类。结果:1979年1月至2011年12月共施行择期肝切除术290例。男性171例(59.0%),女性119例(41.0%)。年龄中位数为63岁,范围1-87岁。总生存期为0 ~ 383个月,中位生存期为31个月。结直肠转移灶行肝切除术患者5年生存率为35.8%(34/95)。讨论。考虑到围手术期和住院死亡率以及5年生存率,肝切除术在小容量中心进行是安全的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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