A dietary supplement containing chlorophytum borivilianum and velvet bean improves sleep quality in men and women.

Integrative medicine insights Pub Date : 2012-01-01 Epub Date: 2012-06-19 DOI:10.4137/IMI.S9720
Cameron G McCarthy, Rick J Alleman, Zach W Bell, Richard J Bloomer
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引用次数: 6

Abstract

Background: Impaired sleep quality is commonplace within industrialized societies, as evidenced by the increasing number of prescription sleep aids available. Certain herbal preparations have been suggested to provide a natural benefit to sleep; however, limited controlled data are available documenting this benefit. In the present study we tested the effect of an experimental dietary supplement, containing the active ingredients Chlorophytum borivilianum and Velvet bean, on sleep quality using the Pittsburgh Sleep Quality Index (PSQI).

Methods: Eighteen healthy and active men and women, with evidence of impaired sleep quality, consumed the supplement daily for 28 days. The PSQI was administered before and after the intervention period. As indicators of safety, resting heart rate and blood pressure were measured, and a complete blood count, comprehensive metabolic panel, and lipid panel were determined.

Results: Sleep quality was influenced by the supplement, as evidenced by an improvement in every category of the PSQI questionnaire (P < 0.05), with most category scores improving approximately 50% from pre to post intervention. No adverse outcomes were noted with use of the supplement, as indicated by no change in resting heart rate, blood pressure, or any bloodborne parameter.

Conclusions: An investigational dietary supplement containing the active ingredients Chlorophytum borivilianum and Velvet bean improves sleep quality in men and women. Additional placebo controlled trials are needed to corroborate these findings in individuals with self-reported sleeping difficulty.

一种含有吊兰和绒豆的膳食补充剂可以改善男性和女性的睡眠质量。
背景:睡眠质量受损在工业化社会中是司空见惯的,越来越多的处方睡眠辅助药物证明了这一点。某些草药制剂被认为对睡眠有天然的好处;然而,有限的受控数据证明了这一好处。本研究采用匹兹堡睡眠质量指数(PSQI)测试了含有绿吊兰和丝绒豆活性成分的实验性膳食补充剂对睡眠质量的影响。方法:18名健康活跃的男性和女性,有证据表明睡眠质量受损,每天服用补充剂28天。在干预前后分别进行PSQI测试。作为安全性指标,测量静息心率和血压,并测定全血细胞计数、综合代谢组和脂质组。结果:补充剂对睡眠质量有影响,PSQI问卷的每个类别得分均有改善(P < 0.05),大多数类别得分从干预前到干预后提高了约50%。使用该补充剂未发现不良后果,静息心率、血压或任何血源性参数均无变化。结论:含有吊兰和丝绒豆活性成分的膳食补充剂可改善男性和女性的睡眠质量。需要更多的安慰剂对照试验来证实这些发现在自我报告睡眠困难的个体中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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