Lymphangioma: Is intralesional bleomycin sclerotherapy effective?

Biomedical imaging and intervention journal Pub Date : 2011-07-01 DOI:10.2349/biij.7.3.e18

Z Rozman, R R Thambidorai, A M Zaleha, Z Zakaria, M A Zulfiqar

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引用次数: 4

Abstract

Purpose: This study aims to evaluate the effectiveness of intralesional bleomycin sclerotherapy in the treatment of lymphangioma in children and to determine the incidence of complications in the treatment.

Methods: This is a retrospective study of 24 children diagnosed with lymphangioma and treated with intralesional injection of bleomycin aqueous solution from January 1999 to December 2004.

Results: Complete resolution was seen in 63% (15/24) of lesions, 21% (5/24) had good response and 16% (4/24) had poor response. The tumour recurred in 2 patients. Two other patients had abscess formation at the site of injection. No other serious complications or side effects were observed.

Conclusion: Intralesional bleomycin therapy was very effective in the treatment of lymphangioma. Our results were comparable to other published studies. Bleomycin administered as intralesional injection was found to be safe as there was no serious complication or side effect observed in this study.

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淋巴管瘤:病变内博来霉素硬化治疗有效吗?

目的:本研究旨在评价病灶内博来霉素硬化疗法治疗儿童淋巴管瘤的疗效，并确定治疗过程中并发症的发生率。方法:回顾性分析1999年1月至2004年12月诊断为淋巴管瘤并病灶内注射博来霉素水溶液治疗的24例患儿。结果:63%(15/24)的病变完全消退，21%(5/24)的病变反应良好，16%(4/24)的病变反应不良。2例肿瘤复发。另外2例患者在注射部位出现脓肿。未见其他严重并发症或副作用。结论:病灶内应用博来霉素治疗淋巴管瘤疗效显著。我们的结果与其他已发表的研究具有可比性。在本研究中，博莱霉素作为病灶内注射是安全的，因为没有观察到严重的并发症或副作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Biomedical imaging and intervention journal

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