[Septic complications after multilocal fractures and multiple traumatic injury].

Robert Okapa, Stanisław Rak, Jarosław Wenda, Wojciech Marczyński, Piotr Walczak, Julia Macias
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Abstract

Introduction: The increase of the number of the multiple traumatic injuries is related to social factors, such as: the development of industry, the change of life style and the conditions of work, the manner and the speed of relocation and the biological factors related with the elongation of life time. According to the World Health Organization data the injuries are one of the main health problems in the world.

Aim: The clinical analysis of multitrauma patients treated due to the septic complications of the fractures.

Material and methods: The material consists of 34 multitrauma patients treated in The Osteomyelitis and Septic Complications Unit in Prof. A. Gruca Orthopedic and Trauma Hospital in Otwock, Poland between 2005 and 2010. The cause of trauma, the timing of arrival to our unit, the number of the days of treatment, the number and the specificity of bone and internal injuries, the bacteriology of bone infections and operative techniques and pharmacologic treatment were analyzed.

Results: The causes of the injuries were: road accident (79%), fall from the height (8.8%), others (12.2%). The first stay in our unit was 21 months after the injury on average (1-129 months), the number of stays in the unit was 2,8 on average (1-6), the length of stay was 25.7 days on average (4-108 days). In analyzed group of 34 patients, we found: 12 opened fractures of single bone, 11 opened fractures of more than one bone, 22 closed fractures of single bone, 12 closed fracture of more than one bone. Central nervous system (55.9%), abdominal organs (35.3%) and thorax (29.4%) were the most common internal organs ocuppied with the injury. Osteomyelitis was the most frequently diagnosed in femur (50%) and tibia (41.2%). The main reasons of bone infection were: Methycylin-Sensitive Staphylococcus Aureus (35,3%), Methycylin-Resistant Staphylococcus Aureus (17,3%), Pseudomonas aeruginosa (23,5%), Escherichia coli, Acinetobacter baumani, Enterococcus faecalis. The following treatment was undertaken: the debridement of septic bone, usually together with the removal of the hardware stabilization (73,5%), the removal of the damaged or improperly fixed stabilization (44%), the conversion of the internal fixation into the external fixation(62%). All the patients were taken intravenous antibiotics according to The Hospital Commission for Preventing of Infections, i.e. 2nd generation cephalosporin and gentamycin. Culture directed antibiotics were started after receiving the bacteriology results. The outcomes. The control of infection in 14 patients (41.3%), 18 patients (52.9%) still remain under the treatment, bad outcome (persistent infection, amputation of a extremity) we had in 2 patients.

Conclusions: Multiple traumatic injury and its immunologic consequences predispose to systemic infections including bone infections. Posttraumatic osteomyelitis is the indication to chronic treatment. Surgical management of the wound and external fixation of the fractures of the long bones according to the control damage surgery is the most important in prevention of posttraumatic osteomyelitis.

[多局部骨折及多处外伤后脓毒性并发症]。
摘要:多重创伤性损伤数量的增加与社会因素有关,如:工业的发展、生活方式和工作条件的改变、迁移的方式和速度以及与寿命延长有关的生物因素。根据世界卫生组织的数据,伤害是世界上主要的健康问题之一。目的:探讨骨折后脓毒性并发症的临床分析。材料和方法:该材料包括2005年至2010年间在波兰Otwock的A. Gruca教授骨科和创伤医院骨髓炎和脓毒性并发症部门治疗的34名多重创伤患者。对创伤的原因、到我单位就诊的时间、治疗天数、骨及内伤的数量和特异性、骨感染的细菌学、手术技术和药物治疗进行了分析。结果:致伤原因为:道路交通事故(79%)、高空坠落(8.8%)、其他(12.2%)。首次住院时间平均为伤后21个月(1-129个月),住院次数平均为2次,8次(1-6次),住院时间平均为25.7天(4-108天)。在分析组34例患者中,发现单骨开放性骨折12例,多骨开放性骨折11例,单骨闭合性骨折22例,多骨闭合性骨折12例。以中枢神经系统(55.9%)、腹部器官(35.3%)和胸腔(29.4%)为最常见的脏器。骨髓炎最常见于股骨(50%)和胫骨(41.2%)。骨感染的主要原因为:甲瓶敏感金黄色葡萄球菌(35.3%)、甲瓶耐药金黄色葡萄球菌(17.3%)、铜绿假单胞菌(23.5%)、大肠杆菌、鲍曼不动杆菌、粪肠球菌。采取以下治疗方法:对化脓性骨进行清创,通常同时取出固定物(73.5%),取出受损或不正确固定的稳定物(44%),将内固定物转为外固定物(62%)。所有患者均按医院感染预防委员会规定静脉注射抗生素,即第二代头孢菌素和庆大霉素。收到细菌学结果后开始定向培养抗生素。结果。感染控制14例(41.3%),仍在治疗的18例(52.9%),2例出现不良结局(持续感染,截肢)。结论:多发创伤及其免疫后果易导致包括骨感染在内的全身性感染。创伤后骨髓炎是指慢性治疗。根据控制性损伤手术对长骨骨折的伤口和外固定进行外科处理是预防创伤后骨髓炎的最重要的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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