Comparison of salivary antioxidants in healthy smoking and non-smoking men.

Chang Gung medical journal Pub Date : 2011-11-01

Hamid-reza Abdolsamadi, Mohammad-taghi Goodarzi, Hamed Mortazavi, Maryam Robati, Fatemeh Ahmadi-Motemaye

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Abstract

Background: Tobacco use is known as a serious global public health problem, and is also an important risk factor for oral diseases. Saliva is the first biological medium encountered during inhalation of cigarette smoke. Therefore, the main aim of this study was to compare the levels of salivary antioxidants between healthy smoking and non-smoking men.

Methods: Unstimulated whole saliva samples were collected from 80 men. Forty subjects were smokers with a daily consumption of 20 cigarettes for at least 10 years and 40 subjects were non-smokers. The salivary levels of uric acid, superoxide dismutase, glutathione peroxidase, and peroxidase were measured and compared between studied groups.

Results: The mean levels of salivary superoxide dismutase, glutathione peroxidase, and peroxidase were significantly lower in smokers than non-smokers. There was no statistically significant difference in the salivary uric acid level between smokers and non-smokers.

Conclusions: Measurement of antioxidant agents in human saliva might be useful for estimating the level of oxidative stress caused by cigarette smoke.

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健康吸烟与非吸烟男性唾液抗氧化剂的比较。

背景:烟草使用被认为是一个严重的全球公共卫生问题，也是口腔疾病的一个重要危险因素。唾液是吸入香烟烟雾时遇到的第一个生物介质。因此，这项研究的主要目的是比较健康吸烟和不吸烟男性的唾液抗氧化剂水平。方法:采集80例男性非刺激全唾液标本。40名受试者是每天吸20支烟至少10年的吸烟者，40名受试者是不吸烟者。测定各组唾液尿酸、超氧化物歧化酶、谷胱甘肽过氧化物酶和过氧化物酶水平并进行比较。结果:吸烟者唾液超氧化物歧化酶、谷胱甘肽过氧化物酶和过氧化物酶的平均水平明显低于非吸烟者。在吸烟者和非吸烟者之间唾液尿酸水平没有统计学上的显著差异。结论:测定人唾液中的抗氧化剂可能有助于估计吸烟引起的氧化应激水平。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Chang Gung medical journal

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