{"title":"Nanomedicine formulations for combination therapies.","authors":"Twan Lammers, Gert Storm, Fabian Kiessling","doi":"10.3402/nano.v1i0.5705","DOIUrl":null,"url":null,"abstract":"Nanomedicine formulations are nanometer-sized carrier materials designed for improving the biodistribution of systemically applied (chemo-) therapeutic drugs. Clinically relevant examples of nanomedicine formulations are liposomes, polymers and micelles. By delivering pharmacologically active agents more selectively to pathological sites (site-specific drug delivery) and/or by guiding them away from potentially endangered healthy tissues (site-avoidance drug delivery), nanomedicine formulations aim to improve the balance between the efficacy and the toxicity of therapeutic interventions. (Published: 8 November 2010) Citation: Nano Reviews 2010, 1 : 5705 - DOI: 10.3402/nano.v1i0.5705","PeriodicalId":74237,"journal":{"name":"Nano reviews","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/nano.v1i0.5705","citationCount":"15","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nano reviews","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3402/nano.v1i0.5705","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2010/11/8 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 15
Abstract
Nanomedicine formulations are nanometer-sized carrier materials designed for improving the biodistribution of systemically applied (chemo-) therapeutic drugs. Clinically relevant examples of nanomedicine formulations are liposomes, polymers and micelles. By delivering pharmacologically active agents more selectively to pathological sites (site-specific drug delivery) and/or by guiding them away from potentially endangered healthy tissues (site-avoidance drug delivery), nanomedicine formulations aim to improve the balance between the efficacy and the toxicity of therapeutic interventions. (Published: 8 November 2010) Citation: Nano Reviews 2010, 1 : 5705 - DOI: 10.3402/nano.v1i0.5705
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
