Count-Rate Performance of the Discovery STE PET Scanner Using Partial Collimation.

Lawrence R Macdonald, Ruth E Schmitz, Adam M Alessio, Scott D Wollenweber, Charles W Stearns, Alexander Ganin, Robert L Harrison, Thomas K Lewellen, Paul E Kinahan
{"title":"Count-Rate Performance of the Discovery STE PET Scanner Using Partial Collimation.","authors":"Lawrence R Macdonald,&nbsp;Ruth E Schmitz,&nbsp;Adam M Alessio,&nbsp;Scott D Wollenweber,&nbsp;Charles W Stearns,&nbsp;Alexander Ganin,&nbsp;Robert L Harrison,&nbsp;Thomas K Lewellen,&nbsp;Paul E Kinahan","doi":"10.1109/NSSMIC.2006.354416","DOIUrl":null,"url":null,"abstract":"<p><p>We investigated the use of partial collimation on a clinical PET scanner by removing septa from conventional 2D collimators. The goal is to improve noise equivalent count-rates (NEC) compared to 2D and 3D scans for clinically relevant activity concentrations. We evaluated two cases: removing half of the septa (2.5D); and removing two-thirds of the septa (2.7D). System performance was first modeled using the SimSET simulation package, and then measured with the NEMA NU2-2001 count-rate cylinder (20 cm dia., 70 cm long), and 27 cm and 35 cm diameter cylinders of the same length. An image quality phantom was also imaged with the 2.7D collimator. SimSET predicted the relative NEC curves very well, as confirmed by measurements, with 2.5D and 2.7D NEC greater than 2D and 3D NEC in the range of ~5-20 mCi in the phantom. We successfully reconstructed images of the image quality phantom from measured 2.7D data using custom 2.7D normalization. Partial collimation shows promise for optimized clinical imaging in a fixed-collimator system.</p>","PeriodicalId":73298,"journal":{"name":"IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium","volume":"4 ","pages":"2488-2493"},"PeriodicalIF":0.0000,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/NSSMIC.2006.354416","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/NSSMIC.2006.354416","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

Abstract

We investigated the use of partial collimation on a clinical PET scanner by removing septa from conventional 2D collimators. The goal is to improve noise equivalent count-rates (NEC) compared to 2D and 3D scans for clinically relevant activity concentrations. We evaluated two cases: removing half of the septa (2.5D); and removing two-thirds of the septa (2.7D). System performance was first modeled using the SimSET simulation package, and then measured with the NEMA NU2-2001 count-rate cylinder (20 cm dia., 70 cm long), and 27 cm and 35 cm diameter cylinders of the same length. An image quality phantom was also imaged with the 2.7D collimator. SimSET predicted the relative NEC curves very well, as confirmed by measurements, with 2.5D and 2.7D NEC greater than 2D and 3D NEC in the range of ~5-20 mCi in the phantom. We successfully reconstructed images of the image quality phantom from measured 2.7D data using custom 2.7D normalization. Partial collimation shows promise for optimized clinical imaging in a fixed-collimator system.

使用部分准直的发现STE PET扫描仪的计数率性能。
我们通过从传统的二维准直器中去除间隔,研究了在临床PET扫描仪上部分准直的使用。与2D和3D扫描相比,目标是提高临床相关活性浓度的噪声等效计数率(NEC)。我们评估了两个病例:切除一半间隔(2.5D);切除三分之二的间隔(2.7D)。首先使用SimSET仿真包对系统性能进行建模,然后使用NEMA NU2-2001计数率圆柱体(直径20 cm)进行测量。(长70厘米),以及直径27厘米和35厘米的圆柱体。用2.7D准直器对图像质量幻影进行成像。SimSET很好地预测了相对NEC曲线,经测量证实,在~5-20 mCi范围内,2.5D和2.7D NEC大于2D和3D NEC。我们使用自定义的2.7D归一化,成功地从测量的2.7D数据中重建了图像质量幻象。在固定准直系统中,部分准直显示了优化临床成像的希望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信