Comparison between types of cancer chemotherapies used in a private and a government-based hospital in Mexico.

David Calderón Guzmán, Hugo Juarez Olguín, Angeles Guevara Zempoalteca, Arturo Juárez Jacobo, Lourdes Segura Abarca, Gerardo Barragán Mejía, Ernestina Hernández García
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Abstract

We have compared the frequency and types of cancer chemotherapies used in a private hospital and in a government-based hospital in Mexico City. A retrospective study was conducted from January 2005 to December 2007, and therapeutic management determined in 415 cases reviewed by the attending physicians of the oncology service. In the government-based hospital, 60 different types of cancer were found among 273 patients diagnosed. Acute lymphoblastic leukemia (ALL) had the greatest incidence (30%), followed by Hodgkin's lymphoma (9%), retinoblastoma (7%), neuroblastoma (6%), and osteosarcoma (6%). The entire number of chemotherapy sessions was 7575. Drugs most frequently employed included etoposide (577), followed by methotrexate (575), vincristine (483), cyclophosphamide (312), and cytarabine (277). The economic status among these patients was mainly of limited resources and represented 80% of the total number of patients. The types of cancer found in the private hospital were similar, however the drugs used were predominantly cyclophosphamide (416), doxorubicin (382), 5-fluorouracil (368), paclitaxel (237) and cisplatin (128). The types of cancer were similar in both hospitals and reflected the incidence among the entire population in Mexico, since acute lymphoblastic leukemia, Hodgkin's lymphoma and retinoblastoma, were the types most represented. However, the treatment schemes differed; the chemotherapeutic agents used in the private hospital were rather more specific but significantly more expensive than those employed in the government hospital.

墨西哥私立医院和公立医院使用的癌症化疗类型的比较。
我们比较了墨西哥城一家私立医院和一家公立医院使用的癌症化疗的频率和类型。从2005年1月到2007年12月进行了一项回顾性研究,肿瘤服务的主治医生对415例病例进行了治疗管理。在这所公立医院,273名确诊患者中发现了60种不同类型的癌症。急性淋巴细胞白血病(ALL)发病率最高(30%),其次是霍奇金淋巴瘤(9%)、视网膜母细胞瘤(7%)、神经母细胞瘤(6%)和骨肉瘤(6%)。化疗的总次数是7575次。最常使用的药物包括依托泊苷(577),其次是甲氨蝶呤(575)、长春新碱(483)、环磷酰胺(312)和阿糖胞苷(277)。这些患者的经济状况主要是资源有限,占患者总数的80%。私立医院发现的癌症类型相似,但使用的药物主要是环磷酰胺(416例)、阿霉素(382例)、5-氟尿嘧啶(368例)、紫杉醇(237例)和顺铂(128例)。两家医院的癌症类型相似,反映了墨西哥全体人口的发病率,因为急性淋巴细胞白血病、霍奇金淋巴瘤和视网膜母细胞瘤是最具代表性的类型。然而,治疗方案有所不同;私立医院使用的化疗药物更具体,但比公立医院使用的化疗药物贵得多。
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