Unusual malignant transformation of recurrent sebaceoma. A case report.

Clinical medicine. Oncology Pub Date : 2008-01-01 Epub Date: 2008-04-15 DOI:10.4137/cmo.s477
Heba Al-Khashnam, Hisham Burezq, Ibrahim Al-Aradi, Humoud Al-Sabah, Khalid Al-Abdulhadi
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引用次数: 5

Abstract

Sebaceoma is a benign tumor composed of incompletely differentiated sebaceous cells of varying degrees of maturity. Sebaceomas was never reported as a known premalignant lesion.This is a report of a sixteen year old boy who presented with a malignant transformation of a recurrent sebaceoma which was excised twice by Moh's surgery. Excision was done with a free margin of 1 cm down to the parotid fascia. Reconstruction was performed on the same set by using cervicofascial flap extending down to the supra-clavicular area. The patient had an uneventful postoperative period apart from distal marginal necrosis of the flap, which healed nicely with conservative measures and daily dressing and was sent to our cancer centre to start his adjuvant radiotherapy.Previous literature stated that sebaceoma is a distinctive benign tumor. We have presented a case of an unusual malignant transformation of a preauricular recurrent sebaceoma. This indicates that sebaceoma does have a potential risk of malignant transformation. We believe that managing recurrent sebaceoma more aggressively with wide local excision and postoperative adjuvant radiotherapy would provide better prognosis.

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复发性皮脂腺瘤的异常恶性转化。一份病例报告。
皮脂瘤是一种由成熟程度不同的未完全分化的皮脂腺细胞组成的良性肿瘤。皮脂腺瘤从未被报道为已知的癌前病变。这是一个16岁的男孩谁提出了恶性转化复发皮脂腺瘤,并通过Moh手术切除了两次。切除的自由边缘向下至腮腺筋膜1厘米。使用颈筋膜瓣向下延伸至锁骨上区,对同一组进行重建。除了皮瓣远端边缘坏死外,患者术后无大碍,经保守措施和日常敷料治疗后愈合良好,并被送往我癌症中心开始辅助放疗。既往文献认为皮脂腺瘤是一种独特的良性肿瘤。我们已经提出了一个不寻常的恶性转化耳前复发皮脂瘤的情况。这表明皮脂腺瘤确实有恶性转化的潜在风险。我们认为更积极地治疗复发性皮脂瘤,局部广泛切除和术后辅助放疗将提供更好的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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