Bone Marrow Micrometastases in Breast Cancer Patients: A Long-Term Follow-up Study.

Clinical medicine. Oncology Pub Date : 2008-01-01 Epub Date: 2008-09-04
Annamaria Molino, Monica Giovannini, Rocco Micciolo, Alessandra Auriemma, Elena Fiorio, Antonio Santo, Gian Luigi Cetto
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Abstract

In 125 early breast cancer patients who underwent multiple bone marrow aspirates, there was no significant difference in terms of disease-free and overall survival after a median follow-up of 163 months between the patients with or without micrometastasis at the time of primary surgery. However, when the time-dependent evolution of the bone marrow aspirates was taken into account, some evidence for a longer disease-free and overall survival was found for the patients with negative bone marrow.

乳腺癌患者骨髓微转移:一项长期随访研究
在125例接受多次骨髓抽吸的早期乳腺癌患者中,在初始手术时有无微转移的患者中位随访163个月后,无病生存期和总生存期无显著差异。然而,当考虑到骨髓抽吸物的时间依赖性进化时,一些证据表明骨髓阴性患者的无病生存期和总生存期更长。
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