The presence of precursors of benign pre-B lymphoblasts (hematogones) in the bone marrow of a paediatric patient with cytomegalovirus infection.

Clinical medicine. Oncology Pub Date : 2008-01-01 Epub Date: 2008-05-20 DOI:10.4137/cmo.s751
F Moreno-Madrid, J Uberos, M Díaz-Molina, A Ramírez-Arredondo, P Jiménez-Gámiz, A Molina-Carballo
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引用次数: 9

Abstract

Hematogones are normal B-lymphoid precursors that multiply in the bone marrow of small children and of adults with ferropenic anaemia, neuroblastoma or idiopathic thrombocytopenic purpura. They are not normally found in peripheral blood, and the immunophenotype is virtually indistinguishable from that of B lymphoblasts. We discuss the case of a 3-month infant with an active cytomegalovirus infection, with hepatitis and pancytopenia associated with 13% hematogones in the bone marrow.

Abstract Image

一例巨细胞病毒感染患儿骨髓中存在良性前b淋巴细胞(造血)前体。
造血细胞是正常的b淋巴细胞前体,在患有缺铁性贫血、神经母细胞瘤或特发性血小板减少性紫癜的儿童和成人骨髓中繁殖。它们通常不存在于外周血中,免疫表型与B淋巴细胞几乎没有区别。我们讨论的情况下,3个月大的婴儿活动性巨细胞病毒感染,肝炎和全血细胞减少相关的13%的造血细胞在骨髓。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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