Atrial fibrillation following cardiac surgery: established and emerging strategies of prevention.

Nasir Shariff, Abdul Aleem, Larry E Jacobs, Christopher Cutitta, Sultan M Siddique, Matthew W Martinez, Martin E Matsumura, Ronald Freudenberger
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Abstract

More than 250,000 patients undergo cardiac surgery every year. Although advances in surgical techniques have reduced the peri-operative morbidity and mortality in these patients, atrial fibrillation persists to commonly occur following these surgeries. Traditional therapies have reduced their occurrence; however there are still a significant number of patients who develop this complication. Newer and non-conventional medications are being studied to reduce this cardiac arrhythmia. This review will elaborate on the patho-physiology, and prevention of this arrhythmia. We also aim to summarize recent investigated and patented medications which may result in more effective strategies for prophylaxis against this cardiac arrhythmia.

心脏手术后心房颤动:已建立的和新兴的预防策略。
每年有超过25万名患者接受心脏手术。尽管手术技术的进步降低了这些患者的围手术期发病率和死亡率,但房颤仍然普遍发生在这些手术后。传统疗法减少了它们的发生;然而,仍有相当数量的患者出现这种并发症。正在研究新的和非传统的药物来减少这种心律失常。本文将对其病理、生理及预防作一综述。我们还旨在总结最近研究和专利的药物,这可能导致更有效的策略预防这种心律失常。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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