{"title":"Caspase and nm23: apoptosis genes linked to the antibacterial response of the Chinese mitten crab.","authors":"Xing-Kun Jin, Wei-Wei Li, Qun Wang","doi":"10.4161/bbug.2.3.15046","DOIUrl":null,"url":null,"abstract":"<p><p>Apoptosis is a central regulatory feature of the immune system, and the most common form of death among immunological cells. However, the function of apoptosis, within the innate immune system of invertebrates, remains largely unknown. For this reason, we investigated the immune functionality of two apoptosis genes, caspase and nm23, in the Chinese mitten crab (Eriocheir sinensis), a commercially important and disease vulnerable aquaculture species. The capase and nm23 transcripts were detected in all examined crab tissue; furthermore, the expression is immuno-responsive and may be linked to immune functionality in crabs. </p>","PeriodicalId":89091,"journal":{"name":"Bioengineered bugs","volume":"2 3","pages":"174-7"},"PeriodicalIF":0.0000,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4161/bbug.2.3.15046","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioengineered bugs","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4161/bbug.2.3.15046","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
Abstract
Apoptosis is a central regulatory feature of the immune system, and the most common form of death among immunological cells. However, the function of apoptosis, within the innate immune system of invertebrates, remains largely unknown. For this reason, we investigated the immune functionality of two apoptosis genes, caspase and nm23, in the Chinese mitten crab (Eriocheir sinensis), a commercially important and disease vulnerable aquaculture species. The capase and nm23 transcripts were detected in all examined crab tissue; furthermore, the expression is immuno-responsive and may be linked to immune functionality in crabs.
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