[Natural history of carpal tunnel syndrome--a review].

Andrzej Zyluk, Piotr Puchalski
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Abstract

The review of the literature on the natural history of the carpal tunnel syndrome is presented. It is shown that the condition is characterised by non-uniform and unpredictable clinical course, in which besides the progressive type of evolution, a regressive one (characterised by spontaneous resolution of symptoms) and type of stable clinical picture (with episodes of exacerbation and resolution of symptoms) exist. Proportion of prevalence of particular types of clinical courses is not precisely estimated, but it appears that at least a half of the cases is of non-progressive type. Non-operative treatment of the condition may be effective in those particular cases, without risk of the development of severe neurological complications as a consequence of impairment of the median nerve. The evidence form analysed studies shows that in carpal tunnel syndrome, the clinical symptoms and signs and nerve conduction disturbances have different natural histories. Clinical features are subjected to greater temporal fluctuations than electrophysiological findings, and they frequently do not correlate one with another. There is not common opinion about efficacy of intervention in extreme carpal tunnel syndrome, characterised by severe conduction disturbances in electrophysiological tests and fixed neurological deficits, however surgical decompression of the carpal tunnel appears to be more promising than decline of the treatment. The natural history of the syndrome occurred in the course of other diseases (or conditions, e.g. pregnancy) is different, depending on the type of the disease itself. In the commonest systemic diseases associated with carpal tunnel syndrome, such as diabetes, hypothyroidism and rheumatoid arthritis, there is not common opinion about their prognostic effect on the natural course of the syndrome.

[腕管综合征的自然史综述]。
回顾文献的自然历史的腕管综合征提出。结果表明,该病的特点是临床过程不均匀和不可预测,除进行性演变外,还存在退行性演变(以症状自发消退为特征)和稳定型临床表现(发作加重和症状消退)。特定类型临床病程的患病率比例不能精确估计,但似乎至少有一半的病例是非进展型的。在这些特殊情况下,非手术治疗可能是有效的,没有因正中神经损伤而产生严重神经系统并发症的风险。分析研究的证据形式表明,腕管综合征的临床症状和体征与神经传导障碍具有不同的自然病史。临床特征受到比电生理结果更大的时间波动的影响,而且它们经常彼此不相关。极端腕管综合征的特点是电生理测试中出现严重的传导障碍和固定的神经功能缺损,对于干预的疗效尚无共识,然而腕管手术减压似乎比减少治疗更有希望。在其他疾病(或条件,如怀孕)过程中发生的综合征的自然史是不同的,这取决于疾病本身的类型。在与腕管综合征相关的最常见的全身性疾病中,如糖尿病、甲状腺功能减退症和类风湿性关节炎,关于它们对腕管综合征自然病程的预后影响尚无共识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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