Virulence characteristics of sucrose-fermenting Vibrio vulnificus strains.

Seong-Jung Kim, Choon-Mee Kim, Sung-Heui Shin
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引用次数: 2

Abstract

We identified 6 sucrose-fermenting Vibrio vulnificus strains and examined their virulence characteristics. They were all encapsulated, motile, capable of producing toxins and utilizing transferrin-bound iron, cytotoxic to cultured cells, and virulent enough to kill mice. They could be definitely identified only by genetic identification methods such as PCR, and not by conventional culture-based identification methods such as API 20E (bioMérieux, France). These results indicate that it is essential to adopt genetic approaches as early as possible in order to avoid misdiagnosis of such strains, especially in clinical situations.

蔗糖发酵创伤弧菌菌株的毒力特性。
我们鉴定了6株蔗糖发酵创伤弧菌,并检测了它们的毒力特性。它们都被包裹起来,能运动,能产生毒素,利用转铁蛋白结合的铁,对培养的细胞有细胞毒性,毒性足以杀死老鼠。它们只能通过PCR等遗传鉴定方法进行明确鉴定,而不能通过API 20E等传统的基于培养的鉴定方法(biomassarieux, France)进行鉴定。这些结果表明,为了避免这些菌株的误诊,特别是在临床情况下,尽早采用遗传学方法是至关重要的。
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来源期刊
Korean Journal of Laboratory Medicine
Korean Journal of Laboratory Medicine 医学-医学实验技术
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