[Analysis of influenza type A(H1N1) antibody levels in different population in Gansu province].

中国疫苗和免疫 Pub Date : 2010-06-01

De-shan Yu, Hong-yu Li, Xu-ming Gao

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Abstract

Objective: To investigate influenza type A(H1N1) antibody levels in 3 different population which included common people, people recovered from be infected with influenza A(H1N1) and people vaccinated influenza type A(H1N1) vaccine in Gansu province in 2009.

Methods: Hemagglutination Inhibition (HI) test, HI test is positive when HI-titer > or = 1:40.

Results: The influenza type A(H1N1) antibody-positive rate of urban population were 3.64% (11/302) and 10.45% (44/421) in Gansu province in August and later November respectively. The antibody-positive rate of people vaccinated after 30 days was 46.13% (131/284), GMT was 1:21.31. 10-15 days after infected by influenza type A(H1N1), HI antibody-positive rate was 87.04%, it rose to 96.40% after 15 days vaccination, and GMT was 1:139.4.

Conclusion: In Gansu, Influenza A H1N1 outbroke firstly among students. Currently, all age groups were reported being infected with the influenza type A H1N1 virus. Only 6.65% of residents were given vaccination, antibody level of influenza type A H1N1 in people was low. Influenza type A(H1N1) virus will continue to spread in Gansu. Strengthening vaccination and improving treatment to serious cases were recommended strategies for influenza type A H1N1 control and prevention.

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甘肃省不同人群甲型H1N1流感抗体水平分析

目的:了解2009年甘肃省普通人群、甲型H1N1流感康复者和接种甲型H1N1流感疫苗人群中甲型H1N1流感抗体水平。方法:血球凝集抑制(HI)试验，HI滴度>或= 1:40为阳性。结果:甘肃省8月和11月下旬城镇人口甲型H1N1流感抗体阳性率分别为3.64%(11/302)和10.45%(44/421)。接种30天后抗体阳性率为46.13% (131/284)，GMT为1:21.31。感染甲型H1N1流感后10 ~ 15天，HI抗体阳性率为87.04%，接种15天后升至96.40%，GMT为1:13 .4。结论:甲型H1N1流感在甘肃省以学生为主。目前，据报告所有年龄组都感染了甲型H1N1流感病毒。居民甲流疫苗接种率仅为6.65%，人群甲流抗体水平较低。甲型H1N1流感病毒将继续在甘肃传播。加强疫苗接种和改善对重症病例的治疗是控制和预防甲型H1N1流感的建议策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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中国疫苗和免疫

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