[Analysis on HBV epidemical trend of people age <20 from rural areas of Zhaodong].

中国疫苗和免疫 Pub Date : 2010-06-01
Feng Wang, Yan-cheng Liu, Kai-li Wang
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Abstract

Objective: By two times investigation to the HBV infection of people age <20 in rural areas in Zhaodong city, to understand the effects of HepB immunigation through analysing the changes of HBsAg, anti-HBs and anti-HBc infectious markers during 1986-2005.

Methods: Cross-sectional study was conducted and the surum samples were collected in 1986 and 2005 respectively. HBsAg, anti-HBs and anti-HBc of the sera with SPRIA were tested.

Results: HBsAg average positive rate of the people age <20 decreased from 8.5% in 1986 to 4.4% in 2005 (chi2 = 10.88, P < 0.01). The anti-HBs average positive rate increased to 43.1% in 2005 from 18.3% in 1986 (chi2 = 130.47, P < 0.01). The anti-HBc average positive rate decreased from 39.9% to 15.1% (chi2 = 122.18, P < 0.01).

Conclusion: The HBV infectious background of the rural population in Zhaodong city is high and the HBV infection rate decreased obviously after HepB inoculation since 1986, but it is still higher than the state average rate. It indicated that the HBV prevention in this district need to be enforced and improved.

赵东市农村20岁以下人群乙型肝炎病毒流行趋势分析
目的:对1986年和2005年两次人群乙肝病毒感染情况进行调查。方法:采用横断面研究方法,分别采集样本。检测SPRIA患者血清的HBsAg、anti-HBs和anti-HBc。结论:肇东市农村人群HBV感染背景较高,自1986年以来接种乙肝疫苗后HBV感染率明显下降,但仍高于全国平均水平。提示本区HBV预防工作有待加强和改进。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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