{"title":"[Analysis on epidemiological and serum effect after vaccination of hepatitis A vaccine (HepA)].","authors":"Jian-ping Li, Zhi-xia Gao, Jian Zhou","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To implement HepA vaccination and analyze epidemiological and serum effect.</p><p><strong>Methods: </strong>The children from 1 to 14 years old were vaccinated HepA since 1992 and the HepA has been integrated into EPI to the children aged 1 year in 1996. The enzyme linked immunnosortbent assay (ELISA) was used to detect Anti-Hepatitis A Virus IgG Antibody (Anti-HAV) to analyze serum effect.</p><p><strong>Result: </strong>HepA coverage rate from 1 to 14 years old was 80% in 1998, and it was > 90% after the year of 2001. The coverage of 1 year old children was 95%. The incidence rate of Hepatitis A reduced continuously. The incidence of whole population reduced from 25.96/100.000 in 1992 to 6.38/100.000 in 1994. In 2007, the incidence of Heptitis A decreased 98.10% compared with the incidence of the year of 1992. Epidemiological feature of Hepatitis A was changed. The positive rate of Anti-HAV was increased after vaccination of Hepatitis A Vaccine.</p><p><strong>Conclusion: </strong>The vaccination strategy for 1 to 14 years old had obviously epidemiological and serum effect.</p>","PeriodicalId":56402,"journal":{"name":"中国疫苗和免疫","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2010-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国疫苗和免疫","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: To implement HepA vaccination and analyze epidemiological and serum effect.
Methods: The children from 1 to 14 years old were vaccinated HepA since 1992 and the HepA has been integrated into EPI to the children aged 1 year in 1996. The enzyme linked immunnosortbent assay (ELISA) was used to detect Anti-Hepatitis A Virus IgG Antibody (Anti-HAV) to analyze serum effect.
Result: HepA coverage rate from 1 to 14 years old was 80% in 1998, and it was > 90% after the year of 2001. The coverage of 1 year old children was 95%. The incidence rate of Hepatitis A reduced continuously. The incidence of whole population reduced from 25.96/100.000 in 1992 to 6.38/100.000 in 1994. In 2007, the incidence of Heptitis A decreased 98.10% compared with the incidence of the year of 1992. Epidemiological feature of Hepatitis A was changed. The positive rate of Anti-HAV was increased after vaccination of Hepatitis A Vaccine.
Conclusion: The vaccination strategy for 1 to 14 years old had obviously epidemiological and serum effect.
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