Promoting innovation in pediatric nutrition.

Dennis M Bier
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Abstract

Truly impactful innovation can only be recognized in retrospect. Moreover, almost by definition, developing algorithmic paths on roadmaps for innovation are likely to be unsuccessful because innovators do not generally follow established routes. Nonetheless, environments can be established within Departments of Pediatrics that promote innovating thinking. The environmental factors necessary to do so include: (1) demand that academic Pediatrics Departments function in an aggressively scholarly mode; (2) capture the most fundamental science in postnatal developmental biology; (3) focus education and training on the boundaries of our knowledge, rather than the almost exclusive attention to what we think we already know; (4) devote mentoring, time and resources to only the most compelling unanswered questions in the pediatric sciences, including nutrition; (5) accept only systematic, evidence-based answers to clinical questions; (6) if systematic, evidence-based data are not available, design the proper studies to get them; (7) prize questioning the answers to further move beyond the knowledge limit; (8) support the principle that experiments in children will be required to convincingly answer clinical questions important to children, and (9) establish the multicenter resources in pediatric scientist training, clinical study design and implementation, and laboratory and instrument technologies required to answer today's questions with tomorrow's methods.

推动儿科营养创新。
真正有影响力的创新只有在回顾时才能得到认可。此外,几乎根据定义,在创新路线图上开发算法路径很可能是不成功的,因为创新者通常不会遵循既定路线。尽管如此,可以在儿科内部建立促进创新思维的环境。这样做所必需的环境因素包括:(1)要求学术儿科以积极的学术模式运作;(2)掌握出生后发育生物学的最基础科学;(3)将教育和培训的重点放在我们知识的边界上,而不是几乎只关注我们认为自己已经知道的东西;(4)将指导、时间和资源只投入到儿科科学中最引人注目的未解问题上,包括营养学;(5)对临床问题只接受系统的、循证的答案;(6)如果没有系统的、基于证据的数据,设计适当的研究来获得这些数据;(7)奖励质疑答案,进一步超越知识极限;(8)支持这样一个原则,即需要在儿童身上进行实验,以令人信服地回答对儿童重要的临床问题;(9)在儿科科学家培训、临床研究设计和实施、实验室和仪器技术等方面建立多中心资源,以用未来的方法回答今天的问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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