Latest developments in the matrics process.

Psychiatry (Edgmont (Pa. : Township)) Pub Date : 2010-06-01

Philip D Harvey, Michael Foster Green, Keith H Nuechterlein

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Abstract

The Measurement and Treatment Research to Improve Cognition in Schizophrenia Research process has led to several developments in the assessment of cognitive functioning for schizophrenia-treatment studies. The first development was the development of a consensus cognitive battery and a United States Food and Drug Administration-endorsed research design. Since the development of the cognitive battery, interest has been spurred in clinical trials in different countries and the development of co-primary functional outcomes measures for these. The MATRICS Consensus Cognitive Battery has been translated into 11 different languages and is being translated into even more. A study has been completed that compared the usefulness of multiple potential co-primary measures, suggesting that the University of California San Diego Performance-Based skills assessment, version II (UPSA-II) is the most suitable for studies conducted in English. These findings suggest that reliable performance-based measures that are easy to administer and highly correlated with cognitive functioning are now available for use in treatment studies.

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矩阵过程的最新发展。

改善精神分裂症认知功能的测量和治疗研究的研究过程导致了精神分裂症治疗研究中认知功能评估的几个发展。第一个发展是共识认知电池的发展和美国食品和药物管理局认可的研究设计。自从认知电池的发展以来，不同国家的临床试验和共同主要功能结果测量的发展激发了人们的兴趣。matrix共识认知电池已经被翻译成11种不同的语言，并且正在被翻译成更多的语言。一项研究已经完成，该研究比较了多种潜在的共同主要措施的有效性，表明加州大学圣地亚哥分校基于绩效的技能评估版本II (UPSA-II)最适合用英语进行的研究。这些发现表明，可靠的基于表现的测量方法易于管理，并且与认知功能高度相关，现在可用于治疗研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Psychiatry (Edgmont (Pa. : Township))

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