[Bacterial multiresistance emergence in South-Western Romania].

Monica Licker, Luminiţa Bădiţoiu, C Negru, Cristina Brînzeu, Roxana Zugravu, F Horhat, Roxana Moldovan
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Abstract

Introduction: European Centre for Diseases Control (ECDC), involved in the surveillance of nosocomial infections (NI) and resistance to antimicrobials (AMR) in Europe, estimates 4 million IN/year, among whom 37,000 deceased, out of which half are determined by multiresistant germs (MDR). A phenomenon encountered more and more often is that of pan-resistance of germs, without the option for an optimal antibiotherapy. The allarming increase of AMR is a phenomenon which our country also faces in the present.

Material, method, results: Resistance rate registered in Intensive Care Units in Timişoara during 2005-2007 (when we participated in the Helics European network) situates us among the last places among the European countries that participated--with 50-60% MRSA strains, 24% E. coli BLSE strains, 62,7% K. pneumoniae BLSE strains, 34% P. aeruginosa BLSE. Furthermore, data registered in ambulatory in the South-West part of Romania during 2006-2007 (processed by the greatest private laboratory in the region) are not more optimistic--26% MRSA strains, 4,25% E. coli BLSE, 12,49% K. pneumoniae BLSE, 8,69% P. aeruginosa BLSE.

Conclusions: As the management of MDR produced infections requires huge costs, a better antibiotic policy in the Romanian hospitals and ambulatory is compulsive, being more efficient to spend for control than for the treatment of these infections.

[罗马尼亚西南部细菌多重耐药的出现]。
导言:欧洲疾病控制中心(ECDC)参与欧洲医院感染(NI)和抗微生物药物耐药性(AMR)的监测,估计每年有400万人感染,其中37,000人死亡,其中一半是由多重耐药细菌(MDR)决定的。越来越多地遇到的现象是细菌的泛耐药,没有最佳抗生素治疗的选择。抗生素耐药性的惊人增长是我国目前面临的一个现象。材料、方法、结果:2005-2007年期间(当我们参加Helics欧洲网络时)在timi oara重症监护病房登记的耐药率使我们在参与的欧洲国家中处于最后的位置- MRSA菌株为50-60%,大肠杆菌BLSE菌株为24%,肺炎克雷伯菌BLSE菌株为62.5%,铜绿假单胞菌BLSE为34%。此外,2006-2007年罗马尼亚西南部地区门诊记录的数据(由该地区最大的私人实验室处理)也不太乐观——MRSA菌株26%,大肠杆菌BLSE 4.25%,肺炎克雷伯菌BLSE 12.49%,铜绿假单胞菌BLSE 8.69%。结论:由于耐多药耐药性产生的感染的管理需要巨大的成本,在罗马尼亚的医院和门诊采取更好的抗生素政策是强制性的,用于控制这些感染比用于治疗这些感染更有效。
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