The efficacy and safety of two fixed combinations: timolol-dorzolamide-brimonidine versus timolol-dorzolamide. A prospective, randomized, double-masked, multi-center, 6-month clinical trial.

Annals of ophthalmology Pub Date : 2009-09-01
Leopoldo Martín Baiza-Durán, Jaime Alvarez-Delgado, Angélica Yussett Contreras-Rubio, Javier Medrano-Palafox, Anel De Luca-Brown, Homero Casab-Rueda, Marco Antonio Cortés-Gastélum, Miguel Jorge Garcidueñas-Mejía, Pedro Gómez-Bastar, Félix Gil-Carrasco, Curt Hartleben-Matkin, Jesús Jiménez-Román, Miguel Luis Moreno-Marín, José Antonio Paczka-Zapata, Gustavo Velasco-Gallegos, Mario Vergara-Sinta
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引用次数: 0

Abstract

We compared the efficacy and safety of a new fixed combination of timolol 0.5%/odorzolamide 20%/brimonidine 0.2% in ophthalmic solution versus a fixed combination of timolol 0.5%/dorzolamide 2% in patients with open-angle glaucoma or ocular hypertension. The fixed triple combination was significantly more efficient in mean intraocular pressure reduction from baseline throughout the six-month follow-up.

替马洛尔-多唑胺-溴莫尼定与替马洛尔-多唑胺两种固定组合的疗效和安全性比较。一项前瞻性、随机、双盲、多中心、为期6个月的临床试验。
我们比较了在开角型青光眼或高眼压患者中,替莫洛尔0.5%/多唑胺20%/溴莫尼定0.2%的新固定组合与替莫洛尔0.5%/多唑胺2%的固定组合的疗效和安全性。在六个月的随访中,固定三联疗法在平均眼压从基线降低方面明显更有效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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Annals of ophthalmology
Annals of ophthalmology 医学-眼科学
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