Pattern of retinopathy of prematurity and its correlation with insulin-like growth factor-1 (IGF-1).

Abstract

We estimated serum insulin-like growth factor-1 (IGF-1) level to correlate for development of retinopathy of prematurity (ROP) in serum from 15 premature infants. 73% of the infant developed Stage 1 ROP and the rest develop Stage 2. Zone III involvement never progress beyond Stage 1, and Zone II beyond Stage 2. Severity of ROP could not be related to the level of IGF-1. All cases develop ROP of Stage 1 and 2 irrespective of serum IGF-1.