Social and Environmental Risk Factors for Hypertension in African Americans.

Selina Rahman, Howard Hu, Eileen McNeely, Saleh M M Rahman, Nancy Krieger, Pamela Waterman, Junenette Peters, Cynthia Harris, Cynthia H Harris, Deborah Prothrow-Stith, Brian K Gibbs, Perry C Brown, Genita Johnson, Angela Burgess, Richard D Gragg
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引用次数: 14

Abstract

This study tests the hypothesis that disparities of hypertension risk in African Americans is related to lead exposure, perceptions of racism, and stress, among urban (Roxbury, MA) and rural (Gadsden, FL) communities. Analysis of preliminary data from Phase I reveal 60% in Gadsden and 39% in Roxbury respondents self-reported having hypertension. In Gadsden 80% people did not know if their residence contained lead paint, compared to 45% in Roxbury. In Gadsden County, 58% of respondents reported experiencing racial discrimination in different settings compared with 72% in Roxbury. In regression analyses high cholesterol emerged as a significant predictors of hypertension in Gadsden County (OR=8.29, CI=1.4-49.3), whereas monthly household income (OR=0.15, CI=0.04-0.7) and diabetes (OR=6.06, CI=1.4-26.17) were significant predictors of hypertension in Roxbury after adjusting for other covariates. These preliminary findings set the stage for initiating Phase II (Phase I continues recruitment), that entail biological marker measurements to rigorously test main hypothesis.

非裔美国人高血压的社会和环境危险因素。
本研究检验了城市(马萨诸塞州罗克斯伯里)和农村(佛罗里达州加兹登)社区中非裔美国人高血压风险差异与铅暴露、种族主义观念和压力有关的假设。第一阶段的初步数据分析显示,Gadsden的60%和Roxbury的39%的受试者自我报告患有高血压。在加兹登,80%的人不知道他们的住所是否含有含铅涂料,而在罗克斯伯里,这一比例为45%。在加兹登县,58%的受访者表示在不同的环境中遭受过种族歧视,而罗克斯伯里的这一比例为72%。在回归分析中,高胆固醇成为Gadsden县高血压的重要预测因子(OR=8.29, CI=1.4-49.3),而在校正其他变量后,家庭月收入(OR=0.15, CI=0.04-0.7)和糖尿病(OR=6.06, CI=1.4-26.17)是Roxbury县高血压的重要预测因子。这些初步发现为启动第二阶段奠定了基础(第一阶段继续招募),这需要生物标记测量来严格检验主要假设。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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