Progressive resistance exercise improves glycaemic control in people with type 2 diabetes mellitus: a systematic review

Casey Irvine , Nicholas F. Taylor
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引用次数: 116

Abstract

Question

Is progressive resistance exercise a safe and effective form of exercise to improve glycaemic control in people with type 2 diabetes?

Design

Systematic review with meta-analysis of randomised controlled trials.

Participants

People with type 2 diabetes mellitus.

Intervention

Progressive resistance exercise.

Outcome measures

The primary outcome was glycaemic control measured as percentage glycosylated haemoglobin (HbA1c). Secondary outcomes were body composition (lean body and fat free mass in kg), and muscle strength (% change in 1RM, dynamometry, change in maximum weight lifted).

Results

The search yielded nine relevant trials that evaluated 372 people with type 2 diabetes. Compared to not exercising, progressive resistance exercise led to small and statistically significant absolute reductions in HbA1c of 0.3% (SMD –0.25, 95% CI –0.47 to –0.03). When compared to aerobic exercise there were no significant differences in HbA1c. Progressive resistance exercise resulted in large improvements in strength when compared to aerobic (SMD 1.44, 95% CI 0.83 to 2.05) or no exercise (SMD 0.95, 95% CI 0.58 to 1.31). There were no significant changes in body composition.

Conclusions

Progressive resistance exercise increases strength and leads to small reductions in glycosylated haemoglobin that are likely to be clinically significant for people with type 2 diabetes. Progressive resistance exercise is a feasible option in the management of glycaemia for this population.

进行性抗阻运动改善2型糖尿病患者的血糖控制:一项系统综述
渐进式抵抗运动是一种安全有效的改善2型糖尿病患者血糖控制的运动形式吗?设计采用随机对照试验的荟萃分析进行系统评价。参与者为2型糖尿病患者。干预:进行性抗阻运动。主要终点是血糖控制,以糖化血红蛋白百分比(HbA1c)衡量。次要结果是身体组成(以kg为单位的瘦体和无脂肪质量)和肌肉力量(1RM变化百分比、动力测量、最大举起重量变化)。研究人员对372名2型糖尿病患者进行了9项相关试验。与不运动相比,渐进式阻力运动导致HbA1c绝对降低0.3% (SMD -0.25, 95% CI -0.47至-0.03)。与有氧运动相比,HbA1c无显著差异。与有氧运动(SMD = 1.44, 95% CI = 0.83 - 2.05)或不运动(SMD = 0.95, 95% CI = 0.58 - 1.31)相比,渐进式阻力运动显著改善了力量。身体成分没有明显变化。进行性阻力运动增加力量,导致糖化血红蛋白的少量减少,这对2型糖尿病患者可能具有临床意义。进行性抗阻运动是这一人群血糖管理的可行选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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