John Pestian, Malik Spencer, Pawel Matykiewicz, Kejian Zhang, Alexander A Vinks, Tracy Glauser
{"title":"Personalizing Drug Selection Using Advanced Clinical Decision Support.","authors":"John Pestian, Malik Spencer, Pawel Matykiewicz, Kejian Zhang, Alexander A Vinks, Tracy Glauser","doi":"10.4137/bii.s2506","DOIUrl":null,"url":null,"abstract":"<p><p>This article describes the process of developing an advanced pharmacogenetics clinical decision support at one of the United States' leading pediatric academic medical centers. This system, called CHRISTINE, combines clinical and genetic data to identify the optimal drug therapy when treating patients with epilepsy or Attention Deficit Hyperactivity Disorder. In the discussion a description of clinical decision support systems is provided, along with an overview of neurocognitive computing and how it is applied in this setting.</p>","PeriodicalId":88397,"journal":{"name":"Biomedical informatics insights","volume":"2 ","pages":"19-29"},"PeriodicalIF":0.0000,"publicationDate":"2009-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/bii.s2506","citationCount":"19","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical informatics insights","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4137/bii.s2506","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 19
Abstract
This article describes the process of developing an advanced pharmacogenetics clinical decision support at one of the United States' leading pediatric academic medical centers. This system, called CHRISTINE, combines clinical and genetic data to identify the optimal drug therapy when treating patients with epilepsy or Attention Deficit Hyperactivity Disorder. In the discussion a description of clinical decision support systems is provided, along with an overview of neurocognitive computing and how it is applied in this setting.