Personalizing Drug Selection Using Advanced Clinical Decision Support.

John Pestian, Malik Spencer, Pawel Matykiewicz, Kejian Zhang, Alexander A Vinks, Tracy Glauser
{"title":"Personalizing Drug Selection Using Advanced Clinical Decision Support.","authors":"John Pestian,&nbsp;Malik Spencer,&nbsp;Pawel Matykiewicz,&nbsp;Kejian Zhang,&nbsp;Alexander A Vinks,&nbsp;Tracy Glauser","doi":"10.4137/bii.s2506","DOIUrl":null,"url":null,"abstract":"<p><p>This article describes the process of developing an advanced pharmacogenetics clinical decision support at one of the United States' leading pediatric academic medical centers. This system, called CHRISTINE, combines clinical and genetic data to identify the optimal drug therapy when treating patients with epilepsy or Attention Deficit Hyperactivity Disorder. In the discussion a description of clinical decision support systems is provided, along with an overview of neurocognitive computing and how it is applied in this setting.</p>","PeriodicalId":88397,"journal":{"name":"Biomedical informatics insights","volume":"2 ","pages":"19-29"},"PeriodicalIF":0.0000,"publicationDate":"2009-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/bii.s2506","citationCount":"19","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical informatics insights","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4137/bii.s2506","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 19

Abstract

This article describes the process of developing an advanced pharmacogenetics clinical decision support at one of the United States' leading pediatric academic medical centers. This system, called CHRISTINE, combines clinical and genetic data to identify the optimal drug therapy when treating patients with epilepsy or Attention Deficit Hyperactivity Disorder. In the discussion a description of clinical decision support systems is provided, along with an overview of neurocognitive computing and how it is applied in this setting.

Abstract Image

Abstract Image

Abstract Image

使用先进的临床决策支持个性化药物选择。
本文描述了在美国领先的儿科学术医疗中心之一开发先进的药物遗传学临床决策支持的过程。这个系统被称为CHRISTINE,结合临床和基因数据来确定治疗癫痫或注意力缺陷多动障碍患者的最佳药物治疗方法。在讨论中,提供了临床决策支持系统的描述,以及神经认知计算的概述以及它如何在这种情况下应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信