Advances in the Nazarov cyclization.

Abstract

Advances in synthetic methodology using the Nazarov reaction, particularly those published since 2005, are reviewed. Three principal subtopics are considered: stereocontrol (both relative and absolute), domino or cascade reactions initiated by the Nazarov cyclization (the 'interrupted Nazarov reaction'), and alternative substrates (including versions of the 'metallo-Nazarov' reaction).