Insulators as mediators of intra- and inter-chromosomal interactions: a common evolutionary theme.

Chin-Tong Ong, Victor G Corces
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引用次数: 28

Abstract

Insulator elements mediate intra- and inter-chromosomal interactions. The insulator protein CCCTC-binding factor (CTCF) is important for insulator function in several animals but a report in BMC Molecular Biology shows that Caenorhabditis elegans, yeast and plants lack CTCF. Alternative proteins may have a similar function in these organisms.

Abstract Image

绝缘子作为染色体内和染色体间相互作用的介质:一个共同的进化主题。
绝缘子元件介导染色体内和染色体间的相互作用。绝缘子蛋白ccctc结合因子(CTCF)在许多动物中对绝缘子功能起重要作用,但《BMC分子生物学》杂志的一篇报道显示秀丽隐杆线虫、酵母和植物缺乏CTCF。替代蛋白在这些生物体中可能具有类似的功能。
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