Duration of anaesthesia, type of surgery, respiratory co-morbidity, predicted VO2max and smoking predict postoperative pulmonary complications after upper abdominal surgery: an observational study

Rebecca L. Scholes , Laura Browning , Ewa M. Sztendur , Linda Denehy
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引用次数: 89

Abstract

Question

Can the risk of developing postoperative pulmonary complications be predicted after upper abdominal surgery?

Design

Prospective observational study.

Participants

268 consecutive patients undergoing elective upper abdominal surgery who received standardised pre- and postoperative prophylactic respiratory physiotherapy.

Outcome measures

Predictors were 17 preoperative and intraoperative risk factors. A postoperative pulmonary complication was diagnosed when four or more of the following criteria were present: radiological evidence of collapse/consolidation, temperature > 38°C, oxyhaemoglobin saturation < 90%, abnormal sputum production, sputum culture indicating infection, raised white cell count, abnormal auscultation findings, or physician's diagnosis of pulmonary complication.

Results

35 participants (13%) developed postoperative pulmonary complications. Five risk factors predicted postoperative pulmonary complications: duration of anaesthesia (OR 4.3, 95% CI 1.7 to 10.8); surgical category (OR 2.3, 95% CI 1.1 to 4.7); current smoking (OR 2.1, 95% CI 1.0 to 4.5); respiratory co-morbidity (OR 2.1, 95% CI 1.0 to 4.4); and predicted maximal oxygen uptake (OR 2.0, 95% CI 1.0 to 4.3). A clinical rule for predicting the development of postoperative pulmonary complications predicted 82% of participants who developed complications. The odds of high risk participants developing pulmonary complications were 8.4 (95% CI 3.3 to 21.3) times that of low risk participants.

Conclusion

This clinical rule for predicting the risk of developing postoperative pulmonary complications from five risk factors may prove useful in prioritising postoperative respiratory physiotherapy. Further research is needed to validate the rule.

麻醉时间、手术类型、呼吸合并症、预测VO2max和吸烟预测上腹部手术后肺部并发症:一项观察性研究
问题:能否预测上腹部手术后发生术后肺部并发症的风险?前瞻性观察性研究。参与者:268例连续接受择期上腹部手术的患者,接受标准化的术前和术后预防性呼吸物理治疗。预后指标为17个术前和术中危险因素。当出现以下四项或以上标准时,诊断为术后肺部并发症:影像学证据显示塌陷/实变,温度和gt;38°C,氧合血红蛋白饱和度;90%,痰量异常,痰培养提示感染,白细胞计数升高,听诊异常,或医生诊断为肺部并发症。结果35例(13%)患者出现术后肺部并发症。预测术后肺部并发症的5个危险因素:麻醉时间(OR 4.3, 95% CI 1.7 ~ 10.8);外科分类(OR 2.3, 95% CI 1.1 ~ 4.7);目前吸烟(OR 2.1, 95% CI 1.0 - 4.5);呼吸道合并症(OR 2.1, 95% CI 1.0 ~ 4.4);并预测最大摄氧量(OR 2.0, 95% CI 1.0 ~ 4.3)。一项预测术后肺部并发症发生的临床规则预测了82%的参与者出现并发症。高风险参与者发生肺部并发症的几率是低风险参与者的8.4倍(95% CI 3.3 ~ 21.3)。结论从5个危险因素预测术后肺部并发症发生风险的临床规律,可用于确定术后呼吸物理治疗的优先级。需要进一步的研究来验证这一规则。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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