Marco Nencioni, Emanuele Asti, Greta Saino, Davide Bona, Stefano Pallotta, Letizia Laface, Luigi Bonavina
{"title":"[Magnetic oesophageal sphincter for the treatment of gastro-oesophageal reflux disease: results of a prospective clinical trial].","authors":"Marco Nencioni, Emanuele Asti, Greta Saino, Davide Bona, Stefano Pallotta, Letizia Laface, Luigi Bonavina","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The authors report the preliminary results of a prospective study in 30 patients with gastro-oesophageal reflux disease. The aim was to assess the efficacy of an-original device designed to augment the lower oesophageal sphincter barrier using magnetic force. The device was placed laparoscopically around the oesophagogastric junction, at the level of the z line identified by intraoperative endoscopy. Transient dysphagia not requiring any treatment was recorded in 45% of patients. At 3 months postoperatively, the GORD-HRQL score was fond to be significantly decreased from 24.4 to 2.2 (p < 0.001) and the DeMeester score was normalised in 80% of patients. At one year follow-up, 100% of patients were off proton pump inhibitors, and 70% of them had a normal DeMeester score. All patients preserved the ability to belch.</p>","PeriodicalId":75700,"journal":{"name":"Chirurgia italiana","volume":"61 2","pages":"187-92"},"PeriodicalIF":0.0000,"publicationDate":"2009-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chirurgia italiana","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The authors report the preliminary results of a prospective study in 30 patients with gastro-oesophageal reflux disease. The aim was to assess the efficacy of an-original device designed to augment the lower oesophageal sphincter barrier using magnetic force. The device was placed laparoscopically around the oesophagogastric junction, at the level of the z line identified by intraoperative endoscopy. Transient dysphagia not requiring any treatment was recorded in 45% of patients. At 3 months postoperatively, the GORD-HRQL score was fond to be significantly decreased from 24.4 to 2.2 (p < 0.001) and the DeMeester score was normalised in 80% of patients. At one year follow-up, 100% of patients were off proton pump inhibitors, and 70% of them had a normal DeMeester score. All patients preserved the ability to belch.
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