Reconstruction mandibulaire en cancérologie : état actuel et perspectives

F. Jegoux , C. Bedfert , N. Alno , G. Le Clech , G. Daculsi
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引用次数: 2

Abstract

Introduction

Mandibular reconstruction in head and neck oncology uses a number of techniques whose results are inconsistent and whose indications do not benefit from consensus.

Materials and methods

A review of the literature allowed us to assemble the available knowledge on current mandibular reconstruction techniques, their functional results, and the research perspectives.

Results and discussion

Marginal resections lead to dental rehabilitation problems, which can be palliated by alveolar enhancement techniques but whose results have not been validated in cases subjected to irradiation. Reconstruction of segmental substance loss is warranted by the repercussions on the vital prognosis when it is anterior and on the quality of life when it is posterior. The ideal means of reconstruction is the free fibular flap, which is limited by cost, morbidity of the donor site, and selection of the patient's surgical team. For these reasons, it may be necessary to turn to pedicled osteo-myocutaneous flaps, abandoned because of their reputedly very high failure rate, but few have been reported in the literature.

Conclusion

Poor functional results of mandibular reconstruction plates make this a last-resort solution. Tissue engineering is currently the most promising line of research. It runs counter to the principles of oncology itself because postoperative radiotherapy reduces the osteoinduction potential of the biomaterials proposed.

下颌重建在癌症学中的现状与展望
头颈部肿瘤的下颌骨重建使用了许多技术,其结果不一致,其适应症也没有得到共识。材料和方法通过对文献的回顾,我们收集了现有的下颌骨重建技术、它们的功能结果和研究前景。结果和讨论边缘切除会导致牙齿康复问题,这些问题可以通过牙槽增强技术得到缓解,但其结果尚未在接受放射治疗的病例中得到验证。部分性物质损失的重建是有必要的,因为它对生命预后的影响,当它是前面的,对生活质量的影响,当它是后面的。游离腓骨瓣是理想的重建方法,但受成本、供区发病率和患者手术团队选择的限制。由于这些原因,可能有必要转向带蒂的骨肌皮瓣,由于其据称失败率很高而被放弃,但文献中很少报道。结论下颌骨重建钢板的修复效果较差,是最后的选择。组织工程是目前最有前途的研究方向。它违背了肿瘤学本身的原则,因为术后放疗降低了所提出的生物材料的骨诱导潜能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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