[Detection of the sensitivity of some bacteria and fungi to the action of sodium phosphotungstate beta-Na6[P2W18O62].18 H2O].

Abstract

Poliyoxometalales are a very special category of the chemical compounds that have multiply properties and possibility to application in a lot of actual domain of the scientific research. One of the most practice application of the polyoxometalates with a special significance is their antibacterial and anti fungus actions. For this study, there have been used fungus, Gram-positive and Gram-negative bacteria, and the action of the polyoxometalates was tested simultaneously with the action of the specifically antibiotics for the studied bacteria. In order to determine the fungus and bacteria sensibility to the tested substance, there have been used three methods: two qualitative, diffusion methods (rondel and bucket methods) and one quantitative method (determination of the minimum inhibitory concentration-MIC). The results of the bucket method were similarly with ones obtained with the rondel method: only Staphylococcus aureus strains were sensitive to the sodium phosphotungstate. Using the quantitative method (MIC) have been emphasized that Pseudomonas aeruginosa and Klebsiella pneumoniae strains were sensitive in time to the studied substance.