[Pulmonary hypertension revealing systemic diseases: two Senegalese case reports].

Dakar medical Pub Date : 2007-01-01
S M Seck, D Dia, M M Cissé, A Guèye, D Diagne, S Fall, S Ndongo, M M Ka, A Kane, T M Diop
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引用次数: 0

Abstract

Introduction: Pulmonary hypertension (PH) is a complication of autoimmune diseases which worsen the prognosis. In Senegal, a few cases of PH have been previously reported in patients with systemic sclerosis.

Case reports: We report two cases of patients with PH that revealed autoimmune diseases (Sharp' syndrome and Sjögren syndrome). Epidemiological, clinical, evolutive and laboratory data were analyzed. Evolution of disease was favourable for one patient and fatal for the other.

Conclusion: These two cases show necessity of early diagnosis of systemic diseases in our countries. PH should be screened in each patient with autoimmune disease before installation of irreversible pulmonary arterial lesions that respond to treatment. New therapy used in idiopathic PH are not yet accessible for our patients.

[揭示全身性疾病的肺动脉高压:两例塞内加尔病例报告]。
肺动脉高压(PH)是自身免疫性疾病的并发症,可使预后恶化。在塞内加尔,以前曾在系统性硬化症患者中报告过一些PH病例。病例报告:我们报告两例患者的PH显示自身免疫性疾病(夏普综合征和Sjögren综合征)。对流行病学、临床、进化和实验室资料进行分析。疾病的进化对一个病人有利,对另一个病人则是致命的。结论:这2例病例说明了我国全身性疾病早期诊断的必要性。在对治疗有反应的不可逆肺动脉病变进行安装之前,应该对每一位自身免疫性疾病患者进行PH筛查。用于特发性PH的新疗法尚未适用于我们的患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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