Dorsal corporectomy in a Ewing sarcoma situated in the pedicle of the L5 vertebral body.

Zentralblatt Fur Neurochirurgie Pub Date : 2008-11-01 Epub Date: 2008-10-23 DOI:10.1055/s-2008-1080938
M Röllinghoff, M Koriller, R Sobottke, K-S Delank, P Eysel
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引用次数: 1

Abstract

The clinical case of a 34-year-old patient is presented who was diagnosed with Ewing sarcoma in the right pedicle of the L5 vertebral body on the basis of persisting dorsolumbar pain. Staging examinations including CT scan of the thorax and abdomen as well as bone scintigraphy were inconspicuous. The patient underwent 6 cycles of neoadjuvant chemotherapy (VIDE, similar to Euro Ewing 99). Presurgically, embolisation of the L4 and L5 vertebral bodies was performed on both sides. The tumour was removed via a dorsal approach with corporectomy of L5 and resection of the right nerve root of L5. The defect was bridged by a titanium cage filled with bone cement; a dorsal L4-S1 instrumentation was performed. Early postoperative X-rays showed a screw dislocation in S1, making a revision intervention and screw replacement necessary. For additional fixation, S2 was instrumented. Histopathology classified the tissue samples as containing no active tumour cells. Surgery was followed by additional chemotherapy. The patient has remained free of recurrence until now. The aim of this case report is to call attention to the unusual site of the Ewing sarcoma as well as to discuss therapy options, especially dorsal corporectomy, and the prognosis together with a review of the most current literature.

位于L5椎体椎弓根的尤文氏肉瘤的背侧切除。
本文报告一34岁患者,因持续腰背部疼痛,被诊断为L5椎体右侧椎弓根尤因肉瘤。分期检查包括胸腹CT扫描和骨显像不明显。患者接受了6个周期的新辅助化疗(VIDE,与Euro Ewing 99相似)。术前,对两侧L4和L5椎体进行栓塞。经背侧入路L5椎体切除术和L5右侧神经根切除术切除肿瘤。缺损用填充骨水泥的钛笼桥接;进行L4-S1背侧内固定。术后早期x光片显示S1螺钉脱位,需要进行翻修干预和更换螺钉。为了进一步固定,S2被固定。组织病理学将组织样本分类为不含活性肿瘤细胞。手术后进行额外的化疗。到目前为止,病人一直没有复发。本病例报告的目的是引起人们对Ewing肉瘤不寻常部位的关注,并讨论治疗方案,特别是椎体背侧切除术,以及预后,同时回顾最新文献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Zentralblatt Fur Neurochirurgie
Zentralblatt Fur Neurochirurgie 医学-神经科学
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