Evaluation of safe and effective administration of nitrous oxide after a postgraduate training course.

Valérie Collado, Emmanuel Nicolas, Denise Faulks, Corinne Tardieu, Marie-Cécile Manière, Dominique Droz, Peter Onody, Martine Hennequin
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Abstract

Background: Conscious sedation is used in dentistry to improve access and quality of care in patients who have difficulty coping with treatment. The aim of this prospective study was to describe a postgraduate training course in conscious sedation for dentists, with specific evaluation of the safe and effective administration of a 50% nitrous oxide in oxygen premix.

Methods: 45 practitioners were trained between 2002 and 2004. They carried out 826 sessions of inhalation sedation in 662 patients. The clinical competency of this group was compared with an expert group.

Results: There was no difference between trainees and experts in ability to complete the planned dental treatment under sedation (89.6% vs 93.2%). Trainees were less successful than experts for patients with intellectual disability (87.4% vs 94.2%, p < 0.01). For both groups, the degree of cooperation improved between initial induction and each perioperative step (Wilcoxon test, p < 0.01). However, for trainees, Venham behaviour scores varied with the type of patient (Kruskal Wallis test, p < 0.001). No major adverse effects were recorded. Trainees reported more minor adverse effects than experts (13% vs. 5.3% respectively, Fisher exact test, p < 0.001)

Conclusion: The trainee practitioners provided effective and safe inhalation sedation. This challenges the current French restriction of the 50% nitrous oxide in oxygen premix to the hospital setting. Further emphasis is required on the teaching of behaviour management skills for patients with intellectual disability.

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在研究生培训课程后对安全有效地使用一氧化二氮进行评估。
背景:在牙科中使用意识镇静法是为了提高难以承受治疗的患者的就诊率和治疗质量。这项前瞻性研究的目的是介绍为牙科医生开设的意识镇静研究生培训课程,并对安全有效地使用含氧 50%的笑气预混剂进行具体评估。他们为 662 名患者实施了 826 次吸入镇静治疗。结果:受训者与专家小组的临床能力没有差异:结果:学员和专家在镇静剂下完成计划牙科治疗的能力方面没有差异(89.6% 对 93.2%)。对于智障患者,学员的成功率低于专家(87.4% vs 94.2%,P < 0.01)。两组患者在初始诱导和围手术期每个步骤之间的合作程度都有所提高(Wilcoxon 检验,P < 0.01)。然而,对于受训者而言,Venham 行为评分因患者类型而异(Kruskal Wallis 检验,p < 0.001)。没有重大不良反应的记录。学员报告的轻微不良反应多于专家(分别为 13% 对 5.3%,费舍尔精确检验,p < 0.001):受训医师提供了有效而安全的吸入镇静。这对目前法国限制在医院环境中使用氧气中含 50%氧化亚氮预混剂的做法提出了挑战。需要进一步重视对智障患者行为管理技能的教学。
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