John C Licciardone, Hollis H King, Kendi L Hensel, Daniel G Williams
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引用次数: 21
Abstract
Background: Osteopathic manipulative treatment (OMT) and ultrasound physical therapy (UPT) are commonly used for chronic low back pain. Although there is evidence from a systematic review and meta-analysis that OMT generally reduces low back pain, there are no large clinical trials that specifically assess OMT efficacy in chronic low back pain. Similarly, there is a lack of evidence involving UPT for chronic low back pain.
Methods: The OSTEOPAThic Health outcomes In Chronic low back pain (OSTEOPATHIC) Trial is a Phase III randomized controlled trial that seeks to study 488 subjects between August 2006 and June 2010. It uses a 2 x 2 factorial design to independently assess the efficacy of OMT and UPT for chronic low back pain. The primary outcome is a visual analogue scale score for pain. Secondary outcomes include back-specific functioning, generic health, work disability, and satisfaction with back care.
Conclusion: This randomized controlled trial will potentially be the largest involving OMT. It will provide long awaited data on the efficacy of OMT and UPT for chronic low back pain.
背景:骨科手法治疗(OMT)和超声物理治疗(UPT)是治疗慢性腰痛的常用方法。虽然有来自系统回顾和荟萃分析的证据表明OMT通常可以减轻腰痛，但没有大型临床试验专门评估OMT对慢性腰痛的疗效。同样，也缺乏关于UPT治疗慢性腰痛的证据。方法:慢性腰痛的骨科健康结果(OSTEOPAThic Health outcomes In Chronic low back pain, OSTEOPAThic)试验是一项III期随机对照试验，在2006年8月至2010年6月期间研究了488名受试者。该研究采用2 × 2因子设计来独立评估OMT和UPT治疗慢性腰痛的疗效。主要结果是疼痛的视觉模拟评分。次要结局包括背部功能、一般健康、工作残疾和对背部护理的满意度。结论:这项随机对照试验可能是涉及OMT的最大的试验。它将提供期待已久的OMT和UPT治疗慢性腰痛疗效的数据。试验报名:http://www.clinicaltrials.gov, NCT00315120。
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