Carbon dioxide microbubbles-enhanced sonographically guided radiofrequency ablation: treatment of patients with local progression of hepatocellular carcinoma.

Radiation medicine Pub Date : 2008-02-01 Epub Date: 2008-02-27 DOI:10.1007/s11604-007-0198-3

Noriyuki Miyamoto, Kazuhide Hiramatsu, Kazuhiko Tsuchiya, Yukihiko Sato

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引用次数: 12

Abstract

Purpose: The aim of our study was to evaluate the usefulness of percutaneous radiofrequency ablation (RFA) using CO2 microbubbles-enhanced sonography for patients with local tumor progression of hepatocellular carcinoma (HCC).

Materials and methods: The tumors of 14 patients with local progression of HCC were treated with CO2 microbubbles-enhanced RFA ablation via a catheter that had been placed in the hepatic artery. We assessed tumor detectability and technical effectiveness. The mean follow-up period was 14.1 months.

Results: Only 6 of the tumors could be found on conventional sonography, whereas 14 tumors were detected on CO2 microbubbles-enhanced sonography. These 14 lesions were successfully treated with RFA guided by CO2 microbubbles-guided sonography. Technical effectiveness was complete in all patients. No serious complications were observed, and there was no local tumor progression during the follow-up period.

Conclusion: RFA guided by CO2 microbubbles-guided sonography is a feasible technique for treating local progression of HCC lesions that cannot be adequately depicted by conventional sonography.

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超声引导下二氧化碳微泡增强射频消融术治疗局部进展的肝细胞癌。

目的:本研究的目的是评估CO2微泡增强超声经皮射频消融(RFA)对局部肿瘤进展的肝细胞癌(HCC)患者的有效性。材料和方法:对14例局部进展的HCC患者进行CO2微泡增强射频消融术治疗，经导管置入肝动脉。我们评估了肿瘤的可检测性和技术有效性。平均随访14.1个月。结果:常规超声仅检出6例肿瘤，CO2微泡增强超声检出14例肿瘤。这14个病变在CO2微泡引导超声引导下的RFA治疗成功。所有患者技术效果完全。随访期间未见严重并发症，局部肿瘤无进展。结论:CO2微泡引导下RFA超声是一种治疗常规超声不能充分描述的肝癌局部进展的可行技术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Radiation medicine

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